Results 21 to 30 of about 93,672 (307)

Aberrant Naive CD4–Positive T Cell Differentiation in Systemic Juvenile Idiopathic Arthritis Committed to B Cell Help

Arthritis & Rheumatology, 2022
Systemic juvenile idiopathic arthritis (JIA) features characteristics of autoinflammation and autoimmunity, culminating in chronic arthritis. In this study, we hypothesized that aberrant or incomplete polarization of T helper cells contributes to disease
J. Kuehn, S. Schleifenbaum, M. Hendling, Sandra Siebenhandl, Julie Krainer, S. Fuehner, A. Hellige, Carolin Park, C. Hinze, H. Wittkowski, D. Holzinger, L. Thurner, A. Weinhäusel, D. Foell, C. Kessel   +14 more
semanticscholar   +1 more source

Experience of use of the anti-cytokine drug adalimumab in children with polyarticular seronegative junior arthritis living in the Samara region

Лечащий Врач, 2023
Background. Juvenile idiopathic arthritis is the most common rheumatic disease in childhood. Adalimumab is the drug of choice for polyarthritis, HLA-B27-associated arthritis, psoriatic arthritis, as well as for the association of arthritis with ...
S. V. Plakhotnikova, G. V. Santalova, Yu. V. Serezhkina, O. V. Sluzhaeva   +3 more
doaj   +1 more source

Transarterial Embolization for Refractory Ankle Synovitis in an Adult Patient With a History of Juvenile Idiopathic Arthritis. [PDF]

ACR Open Rheumatol
Juvenile idiopathic arthritis is a rare but severe childhood‐onset arthritis that carries a high risk of structural joint damage. We report the case of a 32‐year‐old man with a history of juvenile idiopathic arthritis who underwent bilateral hip arthroplasty at age 23 and bilateral ankle arthroplasty at age 24.
Ursini F, Ciaffi J, Peta G, Faldini C, Facchini G.   +4 more
europepmc   +2 more sources

Epidemiology and demographics of juvenile idiopathic arthritis in Africa and Middle East

Pediatric Rheumatology Online Journal, 2021
Juvenile Idiopathic Arthritis (JIA) is a group of chronic heterogenous disorders that manifests as joint inflammation in patients aged
S. Al‐Mayouf, Muna Al Mutairi, K. Bouayed, Sara Habjoka, Djohra Hadef, H. Lotfy, Cristiaan Scott, Elsadeg Sharif, Nouran Tahoun   +8 more
semanticscholar   +1 more source

Growth and puberty in children with juvenile idiopathic arthritis

Pediatric Rheumatology Online Journal, 2021
Juvenile Idiopathic Arthritis is one of the most prevalent chronic diseases in children, with an annual incidence of 2–20 cases per 100,000 and a prevalence of 16–150 per 100,000.
D. M. d’Angelo, Giulia Di Donato, L. Breda, F. Chiarelli   +3 more
semanticscholar   +1 more source

Effect of Clonally Expanded PD‐1highCXCR5–CD4+ Peripheral T Helper Cells on B Cell Differentiation in the Joints of Patients With Antinuclear Antibody–Positive Juvenile Idiopathic Arthritis

Arthritis & Rheumatology, 2021
Antinuclear antibody (ANA)–positive juvenile idiopathic arthritis (JIA) is characterized by synovial B cell hyperactivity, but the precise role of CD4+ T cells in promoting local B cell activation is unknown.
J. Fischer, J. Dirks, J. Klaussner, G. Haase, A. Holl-Wieden, C. Hofmann, S. Hackenberg, H. Girschick, H. Morbach   +8 more
semanticscholar   +1 more source

Risk Factors for the Development of Low Quality of Life in Adults with Juvenile Idiopathic Arthritis

Galician Medical Journal, 2018
Juvenile idiopathic arthritis is known to persist into adulthood which is associated with the development of a large number of long-term consequences, including low quality of life.
Marta Dzhus
doaj   +1 more source

Physical and Mechanical Therapies for Lower Limb Problems in Children With Juvenile Idiopathic Arthritis: A Systematic Review With Meta-Analysis. [PDF]

J Foot Ankle Res
ABSTRACT Objective To systematically review the evidence for physical (for e.g. strengthening) and mechanical (for e.g. foot orthoses) therapies for lower limb problems in children with juvenile idiopathic arthritis (JIA). Methods Randomised clinical trials of physical and mechanical interventions for lower limb problems in children with JIA were ...
Fellas A, Hawke F, Maarj M, Singh-Grewal D, Santos D, Coda A.   +5 more
europepmc   +2 more sources

Systemic juvenile idiopathic arthritis in the pediatric practice of Donetsk region

Regulatory Mechanisms in Biosystems, 2023
Juvenile idiopathic arthritis with systemic onset is a special, rare and the most severe variant of juvenile idiopathic arthritis. The article analyzes the clinical features of the onset and course of juvenile idiopathic arthritis with systemic onset in ...
A. A. Koniushevska, N. V. Vaiser, M. V. Kuzevanova, V. V. Gerasymenko, O. V. Tymoshyna, T. R. Polesova   +5 more
doaj   +1 more source

Golimumab for Polyarticular Juvenile Idiopathic Arthritis and Psoriatic Arthritis: Pharmacologic and Clinical Considerations

Life, 2023
Psoriatic arthritis is a chronic debilitating autoimmune condition, and when diagnosed in patients before the age of eighteen, it is considered pediatric polyarticular juvenile idiopathic arthritis.
Sydney Moore McIntosh, Christian Kerut, Payton P. Hollenshead, Dorothy H. Askins, Kasra Mansourian, Zachary R. Palowsky, Varsha Allampalli, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye   +9 more
doaj   +1 more source