Results 51 to 60 of about 93,672 (307)

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis : Fundamentals Of Care for UveitiS (FOCUS) Initiative [PDF]

open access: yes, 2018
Supplemental material available at www.aaojournal.org. Supported by AbbVie, Inc., and the Fundamentals of Care for Uveitis Initiative National Faculty.
Accorinti, Massimo   +50 more
core   +1 more source

Drug Retention Rate and Predictive Factors of Drug Survival for Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis

open access: yesFrontiers in Pharmacology, 2019
Background and Objectives: Few studies have reported the drug retention rate (DRR) of biologic drugs in juvenile idiopathic arthritis (JIA), and none of them has specifically investigated the DRR of interleukin (IL)-1 inhibitors on systemic JIA (sJIA ...
J. Sota   +19 more
semanticscholar   +1 more source

Optimizing the Start Time of Biologics in Polyarticular Juvenile Idiopathic Arthritis: A Comparative Effectiveness Study of Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans

open access: yesArthritis & Rheumatology, 2021
The optimal time to start biologics in polyarticular juvenile idiopathic arthritis (JIA) remains uncertain. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) developed 3 consensus treatment plans (CTPs) for untreated polyarticular JIA to
Y. Kimura   +11 more
semanticscholar   +1 more source

ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]

open access: yes, 2017
To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De   +9 more
core   +1 more source

Juvenile idiopathic arthritis in infants with Harlequin Ichthyosis: two cases report and literature review

open access: yesItalian Journal of Pediatrics, 2020
Background Harlequin Ichthyosis is the most severe variant of congenital autosomal recessive ichthyosis, associated with severe morbidity and potentially lethal in early life.
Cinzia Auriti   +8 more
doaj   +1 more source

Histopathology of the gut in rheumatic diseases [PDF]

open access: yes, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F.   +4 more
core   +1 more source

Global prevalence estimates of three chronic musculoskeletal conditions: club foot, juvenile idiopathic arthritis and juvenile systemic lupus erythematosus

open access: yesPediatric Rheumatology Online Journal, 2020
Background Musculoskeletal (MSK) conditions are a major source of morbidity and disability. There is a lack of global comparable data on the burden of MSK conditions in children and young people. Our aim was to estimate the global prevalence of three MSK
M. Dave, J. Rankin, M. Pearce, H. Foster
semanticscholar   +1 more source

Cytokine status and hemostasis disorders in children with juvenile idiopathic arthritis

open access: yesActa Biomedica Scientifica
Juvenile idiopathic arthritis is a chronic inflammatory joint disease in children under 16 years of age associated with pathological immune response to various antigens. Probable factors are infectious and immunogenetic.
M. V. Gomellya   +3 more
doaj   +1 more source

THE ROLE OF APOPTOSIS VIOLATIONS IN THE JUVENILE IDIOPATHIC ARTHRITIS FORMATION

open access: yesПедиатрическая фармакология, 2012
We investigated the polymorphism of the gene p53 exon 4 Arg72Pro and intron 3 ins/del 16 b. p. in children with juvenile idiopathic arthritis in order to identify the influence of gene polymorphisms on the course and outcome of the disease.
A. N. Kozhevnikov   +4 more
doaj   +1 more source

Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis: ESSR-ESPR points to consider

open access: yesEuropean Radiology, 2020
Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatic disease. It represents a group of heterogenous inflammatory disorders with unknown origin and is a diagnosis of exclusion in which imaging plays an important role. JIA is defined
R. Hemke   +30 more
semanticscholar   +1 more source

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