Results 111 to 120 of about 1,395 (139)

Juvenile Localized and Systemic Scleroderma

2016
Juvenile localized scleroderma and juvenile systemic sclerosis (jSSc) are sclerotic disorders which differ greatly in their extent of involvement and prognosis. Juvenile localized scleroderma, also called morphea, involves the skin and subcutaneous tissues. It occurs in 4.7–20 per 100,000 children and is ten times more frequent than jSSc. Lesions range
Lauren V. Graham, Amy S. Paller, Ivan Foeldvari   +2 more
openaire   +1 more source

Sarcopenia in juvenile localized scleroderma: new insights on deep involvement

European Radiology, 2020
Juvenile localized scleroderma (JLS) is a rare chronic autoimmune disease which can also affect bones and muscles. Nevertheless, muscle loss was not previously investigated in patients with JLS. Thus, the aim of this study was to retrospectively evaluate deep involvement and assess and quantify sarcopenia in JLS patients using magnetic resonance ...
Silvia Karem Janet Flores Quispe, Annachiara Cavaliere, Michael Weber, Roberto Stramare, Monica Zuliani, Emilio Quaia, Francesco Zulian, Chiara Giraudo   +7 more
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Juvenile Localized Scleroderma

2011
Juvenile localized scleroderma (JLS), known as morphea, comprises a group of conditions which involve essentially the skin and subcutaneous tissues. They have various features and range from very small plaques to extensive fibrotic lesions which may cause significant functional changes and cosmetic deformities.
openaire   +1 more source

Juvenile Localized Scleroderma

Rheumatic Disease Clinics of North America, 2021
Natalia Vasquez-Canizares, Suzanne C. Li
openaire   +1 more source

OP0292 Therapeutic Strategies for Juvenile Localized Scleroderma

Annals of the Rheumatic Diseases, 2015
Background Juvenile localized scleroderma (JLS) is a chronic inflammatory fibrosing disorder with numerous disease subtypes, results in deep tissue atrophy, limited functional capacity. Treatment of jLS is still contraversal, ranges from topical skin management to immunosuppressive therapy (IST).
M. Osminina, N. Geppe, O. Spitonkova, J. Kostina, E. Afonina, G. Tougarinova   +5 more
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[Juvenile localized scleroderma].

Dermatologie (Heidelberg, Germany)
Juvenile scleroderma, often referred to as juvenile localized scleroderma or "morphea", is a rare inflammatory disease of the skin and skin-related structures, accompanied by local sclerosis and tissue fibrosis. Depending on the clinical manifestation, four different subtypes can be defined: limited, generalized, linear, and mixed.
Timmy, Strauss, Claudia, Günther, Normi, Brück   +2 more
openaire   +1 more source

Esophageal involvement in juvenile localized scleroderma: a pilot study.

Clinical and experimental rheumatology, 2007
To evaluate the esophageal involvement in patients with juvenile localized scleroderma (JLS).A cohort of patients with JLS underwent esophageal stationary manometry to evaluate esophageal motility and lower esophageal sphincter (LES) function, distal esophagus 24-hour pH-monitoring to detect gastroesophageal reflux (GER) and upper gastrointestinal (GI)
Guariso G., Conte S., Galeazzi F., Vettorato M. G., Martini G., Zulian F.   +5 more
openaire   +3 more sources

The burden of extracutaneous manifestations in juvenile localized scleroderma: A literature review

Autoimmunity Reviews
Juvenile Localized Scleroderma (JLS) is an autoimmune disease leading to fibrosis of skin and subcutaneous tissues affecting children, that is characterized by extracutaneous manifestations (ECM) in about 20 % of patients. JLS and ECM can cause severe disabilities, potentially impacting patients' quality of life (QoL). We aimed to systematically review
Liguoro I., Simonini G., Martini G.
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[Clinical characteristics of patients with juvenile localized scleroderma].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2011
To investigate the clinical characteristics of juvenile localized scleroderma (JLS).The clinical data of 100 outpatients with JLS who were admitted to PUMC Hospital from 2000 to 2008 were retrospectively analyzed.Of a total of 100 cases, 51 (51%) were confirmed as linear scleroderma, 26 (26%) as plaque morphea, 26 (26%) as deep morphea, 12 (12%) as ...
Qiu-Ning, Sun, Wei, Du, Bin, Hu, Pai, Liu, Xie, Yuan   +4 more
openaire   +1 more source

Juvenile localized scleroderma: A disease with significant morbidity

Journal of the European Academy of Dermatology and Venereology, 2023
openaire   +2 more sources