Results 81 to 90 of about 9,585 (206)

Clinical and laboratory characterization of patients with localized scleroderma and response to UVA-1 phototherapy: In vivo and in vitro skin models [PDF]

, 2022
Background/Purpose Localized scleroderma (LS) is a rare disease leading to progressive hardening and induration of the skin and subcutaneous tissues. LS is responsive to UVA-1 phototherapy, though its exact mechanism of action dermal fibrosis is yet to ...
Carraro, Andrea, Cinotti, Elisa, Guerrini, Giuditta, Mariotti, GIancarlo, Marrocco, Camilla, Rubegni, Pietro, Tognetti, Linda   +6 more
core   +1 more source

The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review [PDF]

, 2017
Autoimmune connective tissue diseases are a heterogeneous group of pathologies that affect about 10% of world population with chronic evolution in 20%-80%.
Costanzo, M., Cupido, F., DI PIAZZA, A., Galia, M., Lagalla, R., LO CASTO, A., LO RE, G., Midiri, F., Midiri, M., Picone, D., Salerno, S., Salvaggi, F., Scopelliti, L., Vernuccio, F.   +13 more
core   +3 more sources

The Role of Abatacept on Inflammation and Fibrosis in Hypochlorous Acid‐Induced Fibrosis Mice

International Journal of Rheumatic Diseases, Volume 28, Issue 5, May 2025.
ABSTRACT Aim To investigate the effect of abatacept in the hypochlorous acid (HCLO)‐induced fibrosis model and to analyze changes in immune cell fractions within the abatacept‐treated early diffuse systemic sclerosis (SSc) cohort. Methods Fibrosis was induced in BALB/c mice by subcutaneous injection of HCLO, and abatacept was injected intraperitoneally
Bingying Dai, Meng Meng, Weilin Chen, Junyu Zhou, Qiming Meng, Liqing Ding, Shasha Xie, Ding Bao, Xiaojing Li, Lijuan Zhao, Ting Huang, Chunliu Lv, Hui Luo, Sijia Liu, Honglin Zhu   +14 more
wiley   +1 more source

Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS): Architecture [PDF]

, 2014
We describe the architecture of the Patient Centered Outcomes Research Institute (PCORI) funded Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS, http://www.SCILHS.org) clinical data research network, which leverages the $48
Adams, William G, Bernstam, Elmer, Bickel, Jonathan, Ge, Yaorong, Hripcsak, George, Klann, Jeffrey G, Kohane, Isaac S, Mandel, Joshua, Mandl, Kenneth D, Marsolo, Keith, McFadden, Douglas, Murphy, Shawn N, Natter, Marc, Ofili, Elizabeth, Perkins, James, Quarshie, Alexander, Schneeweiss, Sebastian, Showalter, John, Weber, Griffin M, Weiler, Sarah, Zhou, Xiaobo   +20 more
core   +2 more sources

Diverse potential of chimeric antigen receptor‐engineered cell therapy: Beyond cancer

Clinical and Translational Medicine, Volume 15, Issue 4, April 2025.
1. In theory, CAR‐engineering therapy can achieve therapeutic effects by targeting cells expressing specific antigens and thereby eliminating or regulating disease‐related cell subpopulations. 2. Although CAR‐engineering therapy is currently only approved for the treatment of cancer, it has also shown potential in non‐tumour diseases. 3.
Lvying Wu, Lingfeng Zhu, Jin Chen
wiley   +1 more source

Сучасні аспекти патогенетичної терапії хворих на склеродермію. Огляд літератури [PDF]

, 2015
Дані літератури свідчать, що традиційні лікарські препарати у хворих на склеродермію ефективні далеко не завжди; багато з них спричиняють різні побічні реакції, що обумовлює пошук принципово нових терапевтичних технологій, у тому числі – з використанням ...
Горбунцов, В.В., Романенко, В.Н., Романенко, К.В.   +2 more
core  

Anti-dense Fine Speckled 70 Autoantibodies in Japanese Children with Dermatomyositis, Localized Scleroderma, and Idiopathic Arthritis with Iridocyclitis [PDF]

, 2017
journal ...
73107, 73108, 73109, 73110, 73111, 73112, AKIYAMA, MASASHI, IWATA, NAOMI, KODERA, MASANARI, KONO, MICHIHIRO, MURO, YOSHINAO, TANAKA, YOSHIHITO   +11 more
core   +1 more source

A Genome‐Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome

Arthritis &Rheumatology, Volume 76, Issue 11, Page 1623-1634, November 2024.
Objective Primary antiphospholipid syndrome (PAPS) is a rare autoimmune disease characterized by the presence of antiphospholipid antibodies and the occurrence of thrombotic events and pregnancy complications. Our study aimed to identify novel genetic susceptibility loci associated with PAPS.
Desiré Casares‐Marfil, Manuel Martínez‐Bueno, Maria Orietta Borghi, Guillermo Pons‐Estel, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Rafaela Ortega‐Castro, Mª Angeles Aguirre‐Zamorano, Alejandro Escudero‐Contreras, Mª Carmen Castro‐Villegas, Yolanda Jiménez Gómez, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Dufour, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Yiannis Ioannou, Chris Chamberlain, Jacqueline Marovac, Marta Alarcón‐Riquelme, Tania Gomes Anjos, Guillermo Reales, Yu Zuo, Gerard Espinosa, Timothy Radstake, Lucas L. van den Hoogen, Chris Wallace, Joel Guthridge, Judith A James, Ricard Cervera, Pier Luigi Meroni, Javier Martin, Jason S. Knight, Marta E. Alarcón‐Riquelme, Amr H. Sawalha   +89 more
wiley   +1 more source

Disabling pansclerotic morphea of childhood with extracutaneous manifestations

Indian Journal of Dermatology, 2013
Disabling pansclerotic morphea (DPM) of childhood is a rare generalized type of localized scleroderma (LS) that is known to follow an aggressive course with pansclerotic lesions leading to severe joint contractures and consequent immobility. Mortality is
Mahendra M Kura, Saurabh R Jindal
doaj   +1 more source

Intravenous treatment of calcinosis cutis with sodium thiosulfate – A case series

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 9, Page 1207-1211, September 2024.
Summary Calcinosis cutis is defined as the deposition of calcium salts in the skin. The dystrophic form is the most common and usually occurs in chronic inflammatory processes associated with collagenoses. Therapeutic options include surgical excision as well as a few pharmacological treatments.
Tom Bruns, Cord Sunderkötter, Johannes Wohlrab   +2 more
wiley   +1 more source