Results 81 to 90 of about 3,332 (178)
Bronchiolitis obliterans. [PDF]
, 1989 Bronchiolitis obliterans in the adult patient is a relatively uncommon and vexing clinical entity. This confusion results because this pathologic finding occurs in a variety of diverse clinical settings.
King, TE
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The Role of Abatacept on Inflammation and Fibrosis in Hypochlorous Acid‐Induced Fibrosis Mice
International Journal of Rheumatic Diseases, Volume 28, Issue 5, May 2025.ABSTRACT Aim To investigate the effect of abatacept in the hypochlorous acid (HCLO)‐induced fibrosis model and to analyze changes in immune cell fractions within the abatacept‐treated early diffuse systemic sclerosis (SSc) cohort. Methods Fibrosis was induced in BALB/c mice by subcutaneous injection of HCLO, and abatacept was injected intraperitoneally
Bingying Dai +14 more
wiley +1 more source
Diverse potential of chimeric antigen receptor‐engineered cell therapy: Beyond cancer
Clinical and Translational Medicine, Volume 15, Issue 4, April 2025.1. In theory, CAR‐engineering therapy can achieve therapeutic effects by targeting cells expressing specific antigens and thereby eliminating or regulating disease‐related cell subpopulations. 2. Although CAR‐engineering therapy is currently only approved for the treatment of cancer, it has also shown potential in non‐tumour diseases. 3.
Lvying Wu, Lingfeng Zhu, Jin Chen
wiley +1 more source
Disabling pansclerotic morphea of childhood with extracutaneous manifestations
Indian Journal of Dermatology, 2013 Disabling pansclerotic morphea (DPM) of childhood is a rare generalized type of localized scleroderma (LS) that is known to follow an aggressive course with pansclerotic lesions leading to severe joint contractures and consequent immobility. Mortality is
Mahendra M Kura, Saurabh R Jindal
doaj +1 more source
Регуляторные пептиды в лечении склеродермии у женщин [PDF]
, 2013 Досліджено ефективність препарату Імфламафертин у комплексній терапії хворих на обмежену склеродермію (ОСД). Представлено результати клінічного та лабораторного дослідження та спостереження 14 жінок, хворих на ОСД.
Горбунцов, В.В. +3 more
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Sexing the X: How the X Became the “Female Chromosome” [PDF]
, 2014 This essay examines how the X became the “female chromosome” and how the association of the X with femaleness influences research questions, models, and descriptive language in human sex chromosome research.
Richardson, Sarah S
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BioMed Research International, Volume 2025, Issue 1, 2025.DNA methylation is an epigenetic mechanism modulating gene expression without altering the genetic sequence and plays a significant role in skin disorders. Methylation patterns on specific genes can lead to either overexpression or suppression, impacting cellular functions critical to skin health.
Anchal Rani +10 more
wiley +1 more source
Prior elicitation of the efficacy and tolerability of Methotrexate and Mycophenolate Mofetil in Juvenile Localised Scleroderma [version 1; peer review: 2 approved] [PDF]
, 2021 Background: Evidence is lacking for safe and effective treatments for juvenile localised scleroderma (JLS). Methotrexate (MTX) is commonly used first line and mycophenolate mofetil (MMF) second line, despite a limited evidence base. A head to head trial
Anderson, Marina E +20 more
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Arthritis &Rheumatology, Volume 76, Issue 11, Page 1623-1634, November 2024.Objective Primary antiphospholipid syndrome (PAPS) is a rare autoimmune disease characterized by the presence of antiphospholipid antibodies and the occurrence of thrombotic events and pregnancy complications. Our study aimed to identify novel genetic susceptibility loci associated with PAPS.
Desiré Casares‐Marfil +89 more
wiley +1 more source
Treatment of systemic sclerosis: potential role for stem cell transplantation. [PDF]
, 2009 Hematopoietic stem cell transplantation may reset the immune reconstitution and induce self tolerance of autoreactive lymphocytes, and has been explored in the treatments for systemic sclerosis.
Derk, Chris T, Xiong, Wen
core +2 more sources