Results 61 to 70 of about 706,173 (166)

Juvenile localized scleroderma: clinical and epidemiological features in 750 children. An international study [PDF]

, 2006
Juvenile localized scleroderma (JLS) includes a number of conditions often grouped together. With the long-term goal of developing uniform classification criteria, we studied the epidemiological, clinical and immunological features of children with JLS ...
MOORE TL, MACHADO C, ZULIAN F, PESERICO STECCHINI NEGRI DE SALVI, ANDREA, LINDSLEY C, ATHREYA BH, VAN SUIJLEKOM SMIT LW, FEITOSA DE OLIVEIRA SK, WOO P, NELSON AM, ESTEVES HILARIO MO, SILVA CA, UZIEL Y, HARPER J, GARCIA CONSUEGRA J, HIGGINS GC, JUVENILE SCLERODERMA WORKING GROUP OF THE PEDIATRIC RHEUMATOLOGY EUROPEAN SOCIETY PRES, CUTTICA R, MARTINI G, GARAY SM, PUNARO MG, LEPORE L, LAXER R, FOELDVARI I   +23 more
core  

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, Volume 6, Issue 1, Page 16-38, March 2026.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]

, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R, Thomas Haberberger, Carol M. Black, Haberberger, T, Xu Shiwen, Martini, G, Holmes, A, Alan Holmes, Andrew Leask, Shiwen, X, David Abraham, Black, CM, Leask, A, Martin, GR, Abraham, D, George R. Martin, Richard Stratton, Giorgia Martini   +17 more
core   +1 more source

Amicrobial Pustulosis of the Folds Successfully Treated With Apremilast: Report of Two Cases and Review of the Literature

The Journal of Dermatology, Volume 53, Issue 2, Page 339-350, February 2026.
ABSTRACT Amicrobial pustulosis of the folds (APF) is a rare, chronic‐relapsing neutrophilic dermatosis characterized by sterile pustules affecting major and minor skin folds. It predominantly affects women and is frequently associated with autoimmune diseases such as systemic lupus erythematosus, inflammatory bowel disease, and autoimmune thyroiditis ...
Luca Bettolini, Carlo Alberto Maronese, Stefano Bighetti, Giovanni Genovese, Luisa Sarno, Stefano Buffon, Francesca Laura Boggio, Federica Derlino, Angelo Valerio Marzano   +8 more
wiley   +1 more source

Localized scleroderma in a cohort of juvenile idiopathic arthritis children [PDF]

Pediatric Rheumatology, 2014
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood. Localized scleroderma also known as morphea is an inflammatory, fibrosing skin disorder that leads to sclerosis of the dermis and eventually of the underlying tissues.
Giani, Teresa, Paganelli, Valeria, Marrani, Edoardo, Gabriele, Simonini, Pagnini, Ilaria, Marino, Achille, Cimaz, Rolando   +6 more
openaire   +1 more source

A Teenage Guitarist's Swollen Fingers

JEADV Clinical Practice, Volume 5, Issue 3, Page 1026-1028, September 2026.
Maho Matsuo, Hiroaki Iwata
wiley   +1 more source

Advances in Novel Therapeutic Strategies for Pulmonary Arterial Hypertension

Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.
Pulmonary arterial hypertension (PAH) is a progressive, life‐threatening disease characterized by vascular remodeling, endothelial dysfunction, and chronic inflammation. Despite existing targeted therapies, long‐term outcomes remain poor, underscoring the need for more effective treatment.
Yalei Wang, Jiacheng Wu, Qian Ma, Hao Chen, Erha Lama, Yulu Yang, Jianwu Huang, Changhu Liu, Xiaofei Ni, Zhihua Qiu, Zihua Zhou, Sami Deniz   +11 more
wiley   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua, Rachel C. Quilang, Katja Sallinger, Christina Athena Aktipis, Petra Arck, Diana W. Bianchi, Hyun‐Dong Chang, Henderson J. Cleaves II, Michael Eikmans, Heidi E. S. Fjeldstad, David Haig, Whitney E. Harrington, William Horsnell, Daniel P. Jacobsen, Mads Kamper‐Jørgensen, Sami B. Kanaan, Kiarash Khosrotehrani, Nathalie C. Lambert, J. Lee Nelson, Maria B. Olsen, Tiffany D. Pan, Jelmer R. Prins, Frank A. Schildberg, Anne Cathrine Staff, Anders Ståhlberg, Ina A. Stelzer, Christopher Urbschat, Sing Sing Way, Melissa A. Wilson, Jody Ye, Thomas Kroneis, Amy M. Boddy   +31 more
wiley   +1 more source

Juvenile Localized Scleroderma from a Pediatric Rheumatology Perspective: A Single-Center Experience

, 2023
Aim: To evaluate juvenile localized scleroderma, which is a disease with high rates of cosmetic and functional sequelae in children, from a pediatric rheumatology perspective.
ÖNER, NİMET, KAPLAN, MELİKE MEHVEŞ, POLAT, MERVE CANSU, ÇELİKEL ACAR, BANU, ÇELİKEL, ELİF, Güngörer, Vildan, KARAGÖL, CÜNEYT, SEZER, MÜGE, COŞKUN, SERKAN, EKİCİ TEKİN, ZAHİDE, AKPINAR TEKGÖZ, PAKİZE NİLÜFER   +10 more
core   +1 more source