Results 81 to 90 of about 2,722 (180)

Disabling pansclerotic morphea of childhood with extracutaneous manifestations

Indian Journal of Dermatology, 2013
Disabling pansclerotic morphea (DPM) of childhood is a rare generalized type of localized scleroderma (LS) that is known to follow an aggressive course with pansclerotic lesions leading to severe joint contractures and consequent immobility. Mortality is
Mahendra M Kura, Saurabh R Jindal
doaj   +1 more source

Studies on the role of autoantibodies and autoantigens in rheumatoid arthritis and myositis [PDF]

, 2016
A major population of patients affected with rheumatoid arthritis (RA) and inflammatory idiopathic myopathies (IIM, collectively called myositis) is characterized by the presence of autoantibodies.
Cerqueira, Cátia
core   +1 more source

Bronchiolitis obliterans. [PDF]

, 1989
Bronchiolitis obliterans in the adult patient is a relatively uncommon and vexing clinical entity. This confusion results because this pathologic finding occurs in a variety of diverse clinical settings.
King, TE
core  

Prior elicitation of the efficacy and tolerability of Methotrexate and Mycophenolate Mofetil in Juvenile Localised Scleroderma [version 1; peer review: 2 approved] [PDF]

, 2021
Background: Evidence is lacking for safe and effective treatments for juvenile localised scleroderma (JLS). Methotrexate (MTX) is commonly used first line and mycophenolate mofetil (MMF) second line, despite a limited evidence base. A head to head trial
Anderson, Marina E, Anton, Jordi, Avcin, Tadej, Beresford, Michael W, Burnett, Thomas, Desai, Yasin, Eleftheriou, Despina, Felton, Jessie, Foeldvari, Ivan, Jacobe, Heidi, Jaki, Thomas, Laguda, Bisola, Leone, Valentina, Li, Suzanne, McErlane, Flora, Mozgunov, Pavel, Pain, Clare E, Ramanan, Athimalaipet V, Shaw, Lindsay, Torok, Kathryn S, Zulian, Francesco   +20 more
core  

Narrowing Down Key Players in Autoimmunity via Single‐Cell Multiomics

European Journal of Immunology, Volume 55, Issue 6, June 2025.
This review explores how single‐cell sequencing and multiomics reveal cell states and communication networks involved in autoimmunity. We highlight insights into antigen specificity and autoreactive lymphocytes, uncovering mechanisms like molecular mimicry.
Altea Gjurgjaj, Cecilia Domínguez Conde
wiley   +1 more source

Esophageal abnormalities in juvenile localized scleroderma: is it associated with other extracutaneous manifestations?

Revista Brasileira de Reumatologia
Objective: To assess esophageal involvement (EI) in juvenile localized scleroderma (JLS) population and the possible association between this gastrointestinal manifestation and demographic data, clinical features, laboratory exams, treatments and ...
Clarissa C.M. Valões, Glaucia V. Novak, Juliana B. Brunelli, Katia T. Kozu, Ricardo K. Toma, Clovis A. Silva   +5 more
doaj   +1 more source

Consensus-based recommendations for the management of juvenile localised scleroderma [PDF]

, 2019
In 2012, a European initiative called Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic and management regimens in Europe for children and young adults with rheumatic diseases ...
Anton, Jordi, Avcin, Tadej, Baildam, Eileen M, Boros, Christina, Chaitow, Jeffrey, Constantin, Tamàs, Culpo, Roberta, Foeldvari, Ivan, Kasapcopur, Ozgur, Knupp Feitosa de Oliveira, Sheila, Pilkington, Clarissa A, Russo, Ricardo, Saad Magalhães, Claudia, Sperotto, Francesca, Toplak, Natasa, van Royen, Annet, Vastert, Sebastiaan J, Wulffraat, Nico M, Zulian, Francesco   +18 more
core   +4 more sources

Регуляторные пептиды в лечении склеродермии у женщин [PDF]

, 2013
Досліджено ефективність препарату Імфламафертин у комплексній терапії хворих на обмежену склеродермію (ОСД). Представлено результати клінічного та лабораторного дослідження та спостереження 14 жінок, хворих на ОСД.
Горбунцов, В.В., Дюдюн, А.Д., Тарнавская, Н.Н., Ющишин, Н.И.   +3 more
core  

Convergent losses of decay mechanisms and rapid turnover of symbiosis genes in mycorrhizal mutualists. [PDF]

, 2015
To elucidate the genetic bases of mycorrhizal lifestyle evolution, we sequenced new fungal genomes, including 13 ectomycorrhizal (ECM), orchid (ORM) and ericoid (ERM) species, and five saprotrophs, which we analyzed along with other fungal genomes ...
Barry, K. W., Kohler, A., Kuo, A., Morin, E., Nagy, László   +4 more
core   +1 more source

Efektivitas Metotreksat sebagai Terapi pada Anak dengan Sistemik Sklerosis

Sari Pediatri
Latar belakang. Sklerosis sistemik juvenil pada anak (JSSc) merupakan penyakit jaringan ikat multisistem, kronis, dan autoimun yang menyerang anak-anak
Charity Cesilia Tololiu, Raynald Oktafianus Takumansang, Diana Devi Sondakh   +2 more
doaj   +1 more source