Results 81 to 90 of about 706,173 (166)

Systemic Sclerosis and Localized Scleroderma in Childhood

, 2008
Juvenile scleroderma syndromes, including the systemic and the localized varieties, represent the third most frequent chronic rheumatic conditions in pediatric rheumatology practice.
Zulian F.
core   +1 more source

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901), Barbara D. Smith (2212672), Takahashi, A, Christopher Denton, Layne, MD, Bahja Ahmed-Abdi, Ayuko Takahashi, Suki, B, Nikitorowicz-Buniak, J, Bela Suki (2212681), Bahja Ahmed-Abdi (2212675), Matthew D. Layne (364786), Markella Ponticos, Ahmed-Abdi, B, Robert Lafyatis, Markella Ponticos (2212669), Xu Shiwen (2212678), Stratton, R, Bela Suki, Barbara D Smith, Richard Stratton (776213), Joanna Nikitorowicz-Buniak (776212), Smith, BD, Christopher Denton (276245), Xu Shiwen, Lafyatis, R, David Abraham (36404), Shiwen, X, David Abraham, Abraham, D, Matthew D Layne, Ponticos, M, Denton, C, Joanna Nikitorowicz-Buniak, Robert Lafyatis (38139), Richard Stratton   +35 more
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A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]

, 2010
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Juvenile Dermatomyositis Research Group, Martin, N, Lucy R. Wedderburn, Sally Smith, Davidson, J.E., Wedderburn, L.R., Smith, S., Neil Martin, Pilkington, C.A., Gardner-Medwin, J. [JD Research Group], Joyce E. Davidson, Krol, P., Petra Krol, Murray, K., Kevin Murray, Clarissa A. Pilkington   +15 more
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Efektivitas Metotreksat sebagai Terapi pada Anak dengan Sistemik Sklerosis

Sari Pediatri
Latar belakang. Sklerosis sistemik juvenil pada anak (JSSc) merupakan penyakit jaringan ikat multisistem, kronis, dan autoimun yang menyerang anak-anak
Charity Cesilia Tololiu, Raynald Oktafianus Takumansang, Diana Devi Sondakh   +2 more
doaj   +1 more source

Renal perfusion in scleroderma patients assessed by microbubble-based contrast-enhanced ultrasound [PDF]

, 2012
OBJECTIVES: Renal damage is common in scleroderma. It can occur acutely or chronically. Renal reserve might already be impaired before it can be detected by laboratory findings.
Himsel, Andrea, Kleinert, Stefan, Roll, Petra, Baumgärtner, Christian, Burkhardt, Harald, Tony, Hans-Peter, Janett, Manfred, Müller, Adelheid, Baumgaertner, Christian, Jenett, Manfred, Fleck, Martin, Feuchtenberger, Martin, Mueller, Adelheid   +12 more
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Juvenile eosinophilic fasciitis: a single center case series

Pediatric Rheumatology Online Journal
Background Eosinophilic fasciitis (EF) is a rare disease characterized by skin induration and musculoskeletal abnormalities. Diagnostic criteria for EF are based on adult populations.
Leigh A. Stubbs, Oluwaseun Ogunbona, Emily Beil, Vibha Szafron, Adekunle Adesina, Sara Anvari, Jamie Lai, Andrea Ramirez, Matthew G. Ditzler, Marietta DeGuzman   +9 more
doaj   +1 more source

Interferons dominate damage and activity in juvenile scleroderma

Objectives Juvenile scleroderma is a heterogeneous group of diseases associated with sclerotic skin lesions, grouped as juvenile systemic sclerosis and juvenile localized scleroderma.
Köse, Hülya, Çekiç, Şükrü, Sarıcaoğlu, Hayriye, Kızmaz, Muhammed Ali, Öztürk, Ferdi, Şimşek, Abdurrahman, Kılıç, Sara Şebnem, Bozkurt, Tuğçe, Budak, Ferah   +8 more
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Methotrexate treatment in juvenile localized scleroderma: a randomized, double-blind, placebo-controlled trial.

, 2011
OBJECTIVE: Juvenile localized scleroderma is a chronic progressive fibrotic disorder of the skin that causes permanent disability and aesthetic damage. This study was undertaken to assess the safety and efficacy of methotrexate (MTX) in the treatment of
Falcini F., Vittadello F, Zulian F, BELLONI FORTINA, ANNA, PATRIZI, ANNALISA, Perilongo G., Paradisi M, Martini G, Torre FL, Paradisi M., Vallongo C, Patrizi A, Alessio M, Vittadello F., Gerloni V, Alessio M., Belloni Fortina A, Patrizi A., Podda R. A., Torre F. L., Belloni-Fortina A., Podda RA, ZULIAN, FRANCESCO, Gerloni V., Falcini F, Zulian F., Martino S., Perilongo G. ., PERILONGO, GIORGIO, Martini G., Belloni Fortina A., La Torre F., ALESSIO, MARIA, Vallongo C., Martino S, Cutrone M, Cutrone M.   +36 more
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The Importance of the Skin Syndrome in the Primary Diagnosis of Connective Tissue Diseases in Children: Case Report

Педиатрическая фармакология
Background. Timely verification of the clinical diagnosis of connective tissue diseases in children based on the onset of the earliest symptoms, including skin manifestations, and timely initiation of treatment can prevent the development of irreversible
Anastasia O. Zatolokina, Tamara V. Belousova, Svetlana A. Loskutova, Nataliya E. Blagitko   +3 more
doaj   +1 more source

Recent Advances in Localized Scleroderma

Sclerosis
Localized scleroderma (LSc), or morphea, is an autoimmune connective tissue disease causing inflammation and fibrosis of the skin and underlying tissues. While distinct from systemic sclerosis, its clinical presentation is highly diverse.
Toshiya Takahashi, Takehiro Takahashi, Yoshihide Asano   +2 more
doaj   +1 more source