Results 51 to 60 of about 706,173 (166)

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple, Sotiria Gizani, Mariano Sanz, Dominique Declerck, Phoebus Madianos, Valerie Clerehugh, Monique Danser, Esti Davidovich, Janet Davies, Nikos Donos, Elisabeth Dursun, Elena Figuero, Filippo Graziani, Mervi Gursoy, Soren Jepsen, Clara Joseph, Moritz Kebschull, Norbert Kraemer, Tina Lambrinaki, Rodrigo López, David J. Manton, Joerg Meyle, Ana Molina, Lior Shapira, Cheryl Somani, Georgios Tsilingaridis, Svante Twetman, Nicola West, Biniyam Wondimu, Ferranti Wong, David Herrera   +30 more
wiley   +1 more source

Endpoints and outcomes for localized scleroderma/morphea: a scoping literature review

Pediatric Rheumatology Online Journal
Background Current treatment for localized scleroderma (LS) has been shown to halt disease activity, but little is still known about patient experiences with these treatments, nor is there consensus about optimal measurement strategies for future ...
Alexy Hernandez, Leslie Zapata Leiva, Maria Mutka, Kathryn S. Torok, Leila Ledbetter, Christina K. Zigler   +5 more
doaj   +1 more source

Provenance legacies override species effects in shaping oak rhizosphere microbiomes and metabolomes

New Phytologist, Volume 251, Issue 1, Page 488-504, July 2026.
Graphical representation of experimental setup. Quercus spp. seeds were collected at two origins: upper Rhine basin (URB) and north German lowland (NGL). Summary As climate change drives more frequent drought‐heat extremes, selecting drought‐tolerant trees is crucial for future forest resilience. However, the role of tree–microbial associations remains
Sebastian Bibinger, Tetyana Nosenko, Prasath Balaji Sivaprakasam Padmanaban, Stefanie Schulz, Hilke Schroeder, Birgit Kersten, Ina Zimmer, Franz Buegger, Michael Schloter, Jörg‐Peter Schnitzler   +9 more
wiley   +1 more source

United Kingdom survey of current management of juvenile localized scleroderma [PDF]

Rheumatology, 2014
Juvenile localized scleroderma (JLS) is a rare condition that is often difficult to assess and for which a variety of monitoring tools have been described. We aimed to describe how monitoring tools are used and perceived by clinicians in the UK, to ascertain treatments used for JLS and to provide a description of transition arrangements to adult care ...
Hawley DP, Pain CE, Baildam EM, Murphy R, Taylor AE, Foster HE   +5 more
openaire   +3 more sources

Successful treatment of severe or methotrexate-resistant juvenile localized scleroderma with mycophenolate mofetil

, 2009
To evaluate the efficacy of mycophenolate mofetil (MMF) in the treatment of severe refractory juvenile localized scleroderma (JLS)
Martini, Giorgia, Goldsmith, Donald P, Zulian, Francesco, Ramanan, Athimalaipet V, Falcini, Fernanda, Girschick, Hermann   +5 more
core   +1 more source

Hand disease in scleroderma: a clinical correlate for chronic hand transplant rejection [PDF]

, 2013
Chronic rejection remains a potential long-term consequence of hand composite tissue allotransplantation (CTA). Scleroderma has already been proposed as a model for chronic facial allograft rejection based on potential parallels of observed progression ...
Puri, A, Butler, PE, Clarke, A, Amin, K; id_orcid, Amin, K, Sivakumar, B, Denton, C   +6 more
core   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Juvenile-onset localized scleroderma activity detection by infrared thermography [PDF]

Rheumatology, 2002
The aim of this study was to define the clinical utility of infrared thermography in disease activity detection in localized scleroderma (LS).We retrospectively reviewed 130 thermal images of 40 children with LS and calculated the sensitivity and specificity of thermography, comparing clinical descriptions of the lesions and contemporary thermographs ...
Martini G., Murray K. J., Howell K. J., Harper J., Atherton D., Woo P., Zulian F., Black C. M.   +7 more
openaire   +4 more sources

Synthetic Nucleic Acid Antigens in Localized Scleroderma [PDF]

, 2023
We investigated the impact of synthetic nucleic acid antigens on the autoantibody profiles in patients with localized scleroderma, an autoimmune skin disease. Anti-DNA antibodies, including double-stranded DNA (dsDNA) and single-stranded DNA (ssDNA), are
Torok, Kathryn S., Bustos, Adrian H., Kathryn S. Torok, Jørgensen, Christian Damsgaard, Gjerdrum, Lise-Mette Rahbek, Rahbek Gjerdrum, Lise Mette, Lise-Mette Rahbek Gjerdrum, Bustos, Adrián Hernández, Kira Astakhova, Bustos, Adrian H, Jørgensen, Christian Damsgaard; id_orcid, Khatri, Sangita, Sangita Khatri, Gjerdrum, Lise Mette Rahbek, Astakhova, Kira, Adrian H. Bustos, Christian Damsgaard Jørgensen   +16 more
core   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source