Clinical Profile of Methotrexate-resistant Juvenile Localised Scleroderma
Methotrexate has demonstrated its efficiency for the treatment of juvenile localized scleroderma but some patients may be resistant. The aim of our study was to define the profile of such patients.
Juliette Hardy +19 more
doaj +2 more sources
Juvenile Scleroderma: A Referral Center Experience
Objectives: This study aims to evaluate the demographic and clinical features, laboratory data, treatment modalities, and outcomes of juvenile systemic sclerosis (JSS) and juvenile localized scleroderma (JLS) patients at a referral pediatric ...
Amra ADROVIC +3 more
doaj +2 more sources
Durometry as an outcome measure in juvenile localized scleroderma. [PDF]
Poff S +4 more
europepmc +4 more sources
Esophageal involvement in juvenile localized scleroderma: a pilot study.
To evaluate the esophageal involvement in patients with juvenile localized scleroderma (JLS).A cohort of patients with JLS underwent esophageal stationary manometry to evaluate esophageal motility and lower esophageal sphincter (LES) function, distal esophagus 24-hour pH-monitoring to detect gastroesophageal reflux (GER) and upper gastrointestinal (GI)
Guariso G. +5 more
openaire +4 more sources
Predictors of Longitudinal Quality of Life in Juvenile Localized Scleroderma. [PDF]
ObjectiveLocalized scleroderma can negatively affect children's quality of life (QoL), but predictors of impact have not been well described. We sought to identify predictors of QoL impact in juvenile localized scleroderma patients.MethodsWe analyzed longitudinal data from a single‐center cohort of juvenile localized scleroderma patients, using ...
Ardalan K, Zigler CK, Torok KS.
europepmc +4 more sources
National Registry for Childhood Onset Scleroderma I: Insights from the first 341 juvenile localized scleroderma patients [PDF]
Kathryn Torok, Haley Havrilla
exaly +2 more sources
Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma. [PDF]
AbstractObjectiveJuvenile localized scleroderma (LS) is a chronic inflammatory skin disorder associated with substantial morbidity and disability. Although a wide range of therapeutic strategies has been reported in the literature, a lack of agreement on treatment specifics and accepted methods for clinical assessment has made it difficult to compare ...
Li SC +24 more
europepmc +4 more sources
Neurological and psychological aspects of scleroderma of the face and neck in children
In the structure of morbidity, among rheumatic diseases in children, juvenile scleroderma takes the third place in frequency after juvenile idiopathic arthritis and systemic lupus erythematosus.
M. S. Pavlova +9 more
doaj +1 more source
OBJETIVO: Avaliar a capilaroscopia periungueal de crianças e adolescentes com doenças reumáticas autoimunes (artrite idiopática juvenil, lúpus eritematoso sistêmico, dermatomiosite juvenil, esclerodermia e doença mista do tecido conjuntivo) e relacioná ...
Daniela Gerent Petry Piotto +3 more
doaj +1 more source
Localized scleroderma – current treatment options
Localized scleroderma (morphea) is a connective tissue disease that affects the skin, subcutaneous tissue and underlying tissues including the fasciae, muscles and bones. The treatment of localized scleroderma depends on the clinical form of the disease,
Małgorzata Michalska-Jakubus +2 more
core +1 more source

