Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center [PDF]
Background Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli +8 more
doaj +4 more sources
Mycophenolate mofetil for methotrexate-resistant juvenile localized scleroderma [PDF]
AbstractObjectivesTo investigate safety and efficacy of MMF in patients with severe or MTX-refractory juvenile localized scleroderma.MethodsConsecutive juvenile localized scleroderma patients undergoing systemic treatment were included in a retrospective longitudinal study.
Zulian Francesco +2 more
exaly +9 more sources
Juvenile localized scleroderma with port wine stain: Coincidental or possible common pathogenetic association [PDF]
Port wine stain and juvenile localized scleroderma are two different dermatoses usually encountered in pediatric age group. Up to now, there are reports of morphea patients initially diagnosed and treated as port wine stain.
Seval Dogruk Kacar +5 more
doaj +3 more sources
Connective tissue nevus misdiagnosed as juvenile localized scleroderma [PDF]
Background Connective tissue nevi (CTN) are congenital hamartomas caused by excessive proliferation of dermis components. In children, CTN can mimic juvenile localized scleroderma (JLS), an immune mediated skin disorder that requires aggressive ...
F. Tirelli +7 more
doaj +5 more sources
Juvenile Localized Scleroderma with Hyaline Deposits in the Renal Arteriole [PDF]
We report a 10-year-old boy with localized scleroderma of the linear and plaque type, who showed proteinuria and hematuria. In this patient, skin, articular, and renal manifestations appeared successively and then began to resolve in the same order.
Nobuko Tabata, Chiyoko Nagano Inoue
doaj +4 more sources
Coexistence of Localized and Systemic Juvenile Scleroderma: A Case Report and Review of Literature [PDF]
Juvenile scleroderma (JS) is a rare chronic connective tissue disorder characterized by progressive fibrosis of the skin and soft tissues with/without internal organ involvements.
Aye Miremarati +4 more
doaj +3 more sources
Juvenile localized scleroderma with autoimmune thyroid disorder [PDF]
Hiremath N +5 more
doaj +4 more sources
New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review [PDF]
Background: Juvenile scleroderma (JS) comprises a group of rare chronic autoimmune and fibrosing disorders in children, primarily presenting as juvenile localized scleroderma (jLS) or juvenile systemic sclerosis (jSS). While jLS predominantly affects the
Chiara Sassetti +5 more
doaj +3 more sources
Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry [PDF]
Objective Localized scleroderma (LS) is a chronic inflammatory and fibrosing skin disorder. We present baseline data on the juvenile LS (jLS) cohort from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry, a multicenter ...
Eveline Y. Wu +6 more
doaj +2 more sources
Juvenile localized scleroderma: review of 44 patients [PDF]
Predominant form of childhood sclerosis is localized scleroderma (LSc) or morphoea. Preliminary classification includes circumscribed morphoea (CM), linear scleroderma (LS), generalized (GM), panclerotic (PM) and mixed morphoea (MM). The major problem in untreated patients is morbidity, so the aim of the therapy is to prevent this.
Iglesias E +7 more
doaj +4 more sources

