Results 21 to 30 of about 706,173 (166)

Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma [PDF]

Pediatric Rheumatology Online Journal, 2018
Objectives To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by ...
Anna Agazzi, Gloria Fadanelli, Fabio Vittadello, Francesco Zulian, Giorgia Martini   +4 more
doaj   +2 more sources

Calcinosis Cutis and Delayed-Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge. [PDF]

Pediatr Dermatol
ABSTRACT A 16‐year‐old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed‐onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis‐specific antibodies, whole‐body MRI revealed extensive subclinical muscle ...
Marrani E, Gatti L, Pagnini I, Oranges T, Filippeschi C, Simonini G.   +5 more
europepmc   +2 more sources

Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity. [PDF]

Clin Transl Med
Nailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
McClellan N, Chen L, Matossian S, Rynda A, Grant K, Janssen E, Kahlenberg JM, Turnier JL.   +7 more
europepmc   +2 more sources

JAK inhibitors for the treatment of juvenile localized scleroderma: a case report and literature review [PDF]

Pediatric Rheumatology Online Journal
Background Juvenile localized scleroderma (JLS) is a chronic autoimmune and fibrosing disease that can cause significant damage and impairments. Currently, management of JLS is challenging due to the paucity of antifibrotic drugs. In patients with severe
Rongjun Zheng, Lixia Zou, Suzanne C. Li, Meiping Lu   +3 more
doaj   +2 more sources

Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study [PDF]

Pediatric Rheumatology Online Journal, 2019
Background We designed and initiated a pilot comparative effectiveness study for juvenile localized scleroderma (jLS), for which there is limited evidence on best therapy.
Suzanne C. Li, Robert C. Fuhlbrigge, Ronald M. Laxer, Elena Pope, Maria F. Ibarra, Katie Stewart, Thomas Mason, Mara L. Becker, Sandy Hong, Fatma Dedeoglu, Kathryn S. Torok, C. Egla Rabinovich, Polly J. Ferguson, Marilynn Punaro, Brian M. Feldman, Tracy Andrews, Gloria C. Higgins, For the CARRA Registry Investigators   +17 more
doaj   +2 more sources

Nailfold Videocapillaroscopy in Pediatric Rheumatology: Established Roles, Emerging Applications, and Future Perspectives [PDF]

Balkan Medical Journal
Nailfold videocapillaroscopy (NVC) provides direct, non-invasive access to the peripheral microcirculation and has become a central tool in adult rheumatology. Its primary clinical value lies in the evaluation of patients presenting with signs of Raynaud
Kübra Öztürk, Fatih Haslak, Mehmet Yıldız, Amra Adrovic, Özgür Kasapçopur   +4 more
doaj   +2 more sources

Long-term methotrexate efficacy in juvenile localized scleroderma [PDF]

Pediatric Rheumatology Online Journal, 2011
Giuliotto S, Zanon G, Vittadello F, Vallongo C, Zulian F, Martini G   +5 more
doaj   +5 more sources

Sarcopenia in juvenile localized scleroderma: new insights on deep involvement

European Radiology, 2020
Juvenile localized scleroderma (JLS) is a rare chronic autoimmune disease which can also affect bones and muscles. Nevertheless, muscle loss was not previously investigated in patients with JLS. Thus, the aim of this study was to retrospectively evaluate deep involvement and assess and quantify sarcopenia in JLS patients using magnetic resonance ...
Silvia Karem Janet Flores Quispe, Annachiara Cavaliere, Michael Weber, Roberto Stramare, Monica Zuliani, Emilio Quaia, Francesco Zulian, Chiara Giraudo   +7 more
openaire   +3 more sources

Revealing Microvascular Involvement in Pediatric Localized Scleroderma Through Nailfold Capillaroscopy [PDF]

Children
Background/Objectives: Juvenile localized scleroderma (jLoS) is a chronic inflammatory disorder with skin and subcutaneous tissue involvement. Microvascular alterations are thought to contribute to its pathogenesis.
Sema Nur Taşkın, Şeyda Doğantan, Esra Esen, Sümeyra Özdemir Çiçek, Ayşenur Paç Kısaarslan, Muammer Hakan Poyrazoğlu   +5 more
doaj   +2 more sources

Localized scleroderma in a newborn (case report) [PDF]

РМЖ. Мать и дитя, 2022
N.I. Akhmina1, P.S. Utkin2, M.P. Shalatonin3, Zh.L. Chabaidze1, A.A. Dement’ev1, A.L. Zaplatnikov1 1Russian Medical Academy of Continuous Professional Education, Moscow,   Russian Federation 2Children’s Infectious Clinical Hospital
N.I. Akhmina, P.S. Utkin, M.P. Shalatonin, Zh.L. Chabaidze, A.A. Dementiev, A.L. Zaplatnikov   +5 more
doaj   +1 more source