Results 61 to 70 of about 56,544 (249)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

A breeding site record of Long-billed Vulture Gyps indicus (Aves: Accipitriformes: Accipitridae) from Bejjur Reserve Forest, Telangana, India

Journal of Threatened Taxa, 2015
The Long-billed Vulture Gyps indicus is, Critically Endangered with few known breeding sites in peninsular India.  We present a previously undocumented Long-billed Vulture breeding site in Bejjur Reserve Forest, Adilabad District, northern Telangana.
Swetha Stotrabhashyam, Bharath Reddy, Venugopal Satla, Imran Siddiqui   +3 more
doaj   +1 more source

Facilitating Expedited Drug Approval– the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, Accepted Article.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Small and large spatial scale coexistence of ctenid spiders in a neotropical forest (French Guiana)

Tropical Zoology, 2018
While spiders constitute the most abundant and diverse arthropods in many habitats, they remained under-studied, especially in tropical rainforests. The goal of this study is to assess the spatial distribution of the spider family Ctenidae by assessing ...
Julien Pétillon, Boris Leroy, El Aziz Djoudi, Vincent Vedel   +3 more
doaj  

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Performance of pacu (Colossoma macropomum) fed varying dietary inclusion levels of fish visceral and duckweed (Lemna minor) as replacement for fish and soybean meals

Journal of Agriculture and Rural Development in the Tropics and Subtropics
The performance of Colossoma macropomum subjected to a six-month feeding trial using duckweed (Lemna minor) and fish visceral as partial replacements for soybean meal and fishmeal respectively was evaluated in this study.
Christopher Nnamdi Onwuka, Oghenefejiro Adagha, Jovita Oghenenyerhovwo Sanubi, Hardin Aaron Jn Pierre, Maureen Onwuka, Simon Obieh   +5 more
doaj   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Juvenile growth of white mullet Mugil curema (Teleostei: Mugilidae) in a coastal lagoon southwest of the Gulf of California Crecimiento de juveniles de la lisa blanca Mugil curema (Teleostei: Mugilidae) en una laguna costera del suroeste del golfo de California

Latin American Journal of Aquatic Research, 2011
Otolith micro structure was used to determine the age and evaluate the growth of juvenile white mullet (Mugil curema) during their residence in the coastal lagoon El Conchalito, B.C.S., Mexico, from May 1997 to May 1998.
Casimiro Quiñonez-Velázquez, Juan Ramón López-Olmos   +1 more
doaj  

JUVENILE LAW REFORM - RETROSPECTIVE AND CONTEMPORARY PERSPECTIVES [PDF]

Probacja
The system of Polish law on juvenile proceedings has undergone significant changes over the years. The result of these changes is the currently in force Act of 9 June 2022 on the support and re-socialisation of minors, which replaced, after 40 years, the
Edyta Mucha
doaj   +1 more source