Results 41 to 50 of about 89,657 (311)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Abundance and distribution of Bregmacerotidae (Pisces) larvae in Campeche Bay, Mexico

open access: yesCiencias Marinas, 1994
The abundance and distribution of larvae and juveniles of the family Bregmacerotidae were studied at Campeche Bay (Mexico). The material was obtained from eight oceanographic cruises carried out between March 1981 and August 1988, covering the four ...
F Zavala-García, C Flores-Coto
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Unravelling Seascape Patterns of Cryptic Life Stages: Non-Reef Habitat Use in Juvenile Parrotfishes

open access: yesDiversity, 2020
Juvenile fish often use alternative habitats distinct from their adult phases. Parrotfishes are an integral group of coral reef fish assemblages, are targeted in fisheries, are sensitive to reef disturbances, and have been documented as multiple-habitat ...
Katie T. Sievers   +3 more
doaj   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij   +8 more
wiley   +1 more source

Estimation of abundance for migrating juvenile pink salmon in the rivers of Sakhalin and Iturup Islands in 2023

open access: yesИзвестия ТИНРО
Number of juvenile pink salmon migrated from the spawning grounds in the rivers of East Sakhalin (Dagi, Malaya Khuzi, Kholodny (tributary of Poronay), Lazovaya, Pugachevka, Voznesenka, Ochepukha, Taranai, and Kura) and Iturup Island (Rybatskaya and Olya)
A. M. Kaev   +5 more
doaj   +1 more source

Composition of shrimp populations (Crustacea: Decapoda) in non-vegetated areas of two river islands in a Brazilian Amazon estuary

open access: yesZoologia (Curitiba), 2013
This study investigates the shrimp found in non-vegetated areas of an estuary of the Amazon River. We ascertained the input of juveniles, species' biometrics and the influence of environmental factors on the abundance of species.
Priscila Sousa Vilela da Nóbrega   +2 more
doaj   +1 more source

Animal community dynamics at senescent and active vents at the 9° N East Pacific Rise after a volcanic eruption [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Gollner, S., Govenar, B., Arbizu, P. M., Mullineaux, L.
Arbizu, P. Martinez   +8 more
core   +2 more sources

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang   +7 more
wiley   +1 more source

Estimation of abundance for the migrating juvenile pink salmon in the rivers of Sakhalin and Iturup Islands in 2024

open access: yesИзвестия ТИНРО
Pink salmon is the leading object of salmon fishery in the Sakhalin-Kuril region. To forecast the status of its stocks, the number of juveniles migrated downstream was counted in the rivers Dagi, Malaya Khuzi, Pugachevka, Voznesenka, Ochepukha, Taranai ...
A. M. Kaev, P. S. Sukhonos
doaj   +1 more source

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