Results 41 to 50 of about 73,773 (231)

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao   +9 more
wiley   +1 more source

Maskulinitet og køn [PDF]

open access: yes, 2023
Denne artikel introducerer til studiet af maskulinitet og køn. Først præsenterer jeg relevansen af maskulinitetstemaet for samfundsfagsundervisningen samt de potentialer og faldgruber der overordnet set eksisterer i relation til emnet mænd som socialt ...
Reinicke, Kenneth
core  

Molecular mechanism of central nervous system repair by the Drosophila NG2 homologue kon-tiki

open access: yesJournal of Cell Biology, 2016
Glial cells help central nervous system injury repair, but this is limited by the failure of newly produced glial cells to differentiate. Here, Losada-Perez et al.
María Losada-Pérez   +2 more
semanticscholar   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

open access: yesAdvanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida   +4 more
wiley   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

open access: yesAdvanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng   +12 more
wiley   +1 more source

Giver kvinder og mænd forskellige karakterer? Køn og karaktergivning på universitetet

open access: yesDansk Universitetspaedagogisk Tidsskrift, 2014
Er kvindelige universitetsansatte mere orienteret mod at hjælpe den enkelte studerende end deres mandlige kolleger, og giver de derfor bedre karakterer?
Lotte Bøgh Andersen   +1 more
doaj   +2 more sources

Epitope‐Resolved Digital SERS Profiling of Structurally Dynamic Antigens via a Multi‐Epitope Bispecific Antibody Framework

open access: yesAdvanced Science, EarlyView.
A multi‐epitope digital surface‐enhanced Raman spectroscopy framework enables epitope‐resolved immunoprofiling by integrating bispecific antibody fragments with spectrally encoded nanotags. This approach decouples binding events into independent digital channels, allowing structure‐aware antigen analysis.
Jing Wang   +4 more
wiley   +1 more source

Dette nummers samlede anmeldelser

open access: yesKvinder, Køn & Forskning, 2015
Leta Hong Fincher: Leftover Women: The Resurgence of Gender Inequality in China. Zed Books Ldt, 2014Engebretsen, Elisabeth L.: Queer Women in Urban China: An Ethnography. New York and London: Routledge, 2014Jung Chang: Empress Dowager Cixi. The concubine
Cancan Wang   +3 more
doaj   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li   +11 more
wiley   +1 more source

De læste og læsende køn - refleksioner over køn, litteratur og undervisning

open access: yesKvinder, Køn & Forskning, 1999
The article discusses three different tendencies of research in gender and literature. These are presented as sex, referring to the way we categorise women and men as biological beings; gender as construction; and deconstrudtion of gender binaries. These
Susanne V. Knudsen
doaj   +1 more source

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