Results 51 to 60 of about 73,773 (231)

Highly Efficient Computation of the Basal kon using Direct Simulation of Protein–Protein Association with Flexible Molecular Models

Journal of Physical Chemistry B, 2015
An essential baseline for determining the extent to which electrostatic interactions enhance the kinetics of protein–protein association is the “basal” kon, which is the rate constant for association in the absence of electrostatic interactions. However,
A. S. Saglam, L. Chong
semanticscholar   +1 more source

Flexible Thin‐Film Heater Composed of Laser‐Induced Graphene and Poly(D, L‐Lactic Acid) with Electro‐ and Photo‐Thermal Properties toward Cancer Thermotherapy

Advanced Electronic Materials, EarlyView.
This study introduces a thin‐film‐type heat‐generating device that uses laser induced graphene (LIG) on a poly(D, L‐lactic) acid film, which realizes both resistance heating by direct current application and photothermal conversion heating by near‐infrared light irradiation.
Masato Saito, Sota Harada, Ran Imai, Kon Son, Toshinori Fujie   +4 more
wiley   +1 more source

Abraham Kuyper as kerkregkundige

In die Skriflig, 1989
As partyman was Kuyper onbetwis Abraham die Geweldige. As kerk­regkundige was hy die man vir sintese, die man wat teenstellende filosofiee en teologiese strominge met sy verstommende intellektuele vermoe kon absorbeer en dit dan tot ’n nuwe weg kon ...
C. J. Smit
doaj   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

Racialisering og ordblindhed

Tidsskrift for Professionsstudier, 2023
Ordblindhed menes at være den mest almindelige indlæringsvanskelighed i skolealderen, men de såkaldte ”tosprogede elever” med diagnosticeret ordblindhed er underrepræsenteret i folkeskolen (Gellert 2009).
Hatice Filikci, Jin Hui Li
doaj  

Motstånd och neutralisering. Kön, makt och professionalitet i arbetet med våld i nära relationer

, 2016
Konsintegrerade verksamheter som tar emot kvinnor, man och barn med erfarenheter av vald i nara relationer blir allt vanligare. Artikeln belyser hur arbetet vid en sadan enhet sker i ett spanningsfalt av vald, makt och kon som gor det svart att ...
Tina Mattsson
semanticscholar   +1 more source

Ferroptosis as a p53-mediated activity during tumour suppression

Nature, 2015
Although p53-mediated cell-cycle arrest, senescence and apoptosis serve as critical barriers to cancer development, emerging evidence suggests that the metabolic activities of p53 are also important.
Le Jiang, N. Kon, Tongyuan Li, Shang-Jui Wang, T. Su, H. Hibshoosh, R. Baer, W. Gu   +7 more
semanticscholar   +1 more source

Clinical Validation of a QSP Model for ISB 2001, a Trispecific T Cell Engager to Support Optimal FIH Study Design in RRMM Patients

Clinical Pharmacology &Therapeutics, EarlyView.
ISB 2001 is a trispecific antibody that binds to two tumor‐associated antigens (TAA), CD38 and BCMA, and crosslinks to CD3 on T cells resulting in T cell‐mediated cytotoxicity of tumor cells expressing these TAAs. ISB 2001 is currently being tested in relapsed and/or refractory multiple myeloma (RRMM) patients in the first‐in‐human (FIH) TRIgnite‐1 ...
Vinu Chandralayam Ayyappa Menon, Tomomi Matsuura, Beata Holkova, Girish S. Gudi, Adam Drake, Maria Pihlgren, Piet H. van der Graaf, Sunitha GN, Andrew Garton, Mario Perro, Cyril Konto, Lida Pacaud   +11 more
wiley   +1 more source

Køn

, 2012
Grundbog til litteratur i 37 tematisk ordnede kapitler, hvoraf mit bidrag omhandler "Køn"
Heede, Dag
core   +1 more source

Sekulariteter : förstahet genom religion och kön

, 2018
Secularities – firstness through religion and genderIn this article we explore how the positing religion as other simultaneously makes secularism a firstness.
Linda Berg, Mikela Lundahl, Lena Martinsson   +2 more
semanticscholar   +1 more source