Results 71 to 80 of about 3,058 (95)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1459-1476, August 2026.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1442-1451, August 2026.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Epitope‐Resolved Digital SERS Profiling of Structurally Dynamic Antigens via a Multi‐Epitope Bispecific Antibody Framework

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
A multi‐epitope digital surface‐enhanced Raman spectroscopy framework enables epitope‐resolved immunoprofiling by integrating bispecific antibody fragments with spectrally encoded nanotags. This approach decouples binding events into independent digital channels, allowing structure‐aware antigen analysis.
Jing Wang   +4 more
wiley   +1 more source

Usynligt? Det professionelle blik på køn og kropslig materialitet i daginstitutioner

open access: yesTidsskrift for Professionsstudier
The article addresses questions of gender and bodily materiality  and how this is included in professional practice in Danish ECEC. Point of departure is the finding that professionals are required to include gender equality and equal opportunities for ...
Jo Krøjer
doaj  

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2885-2898, August 2026.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Clinical Validation of a QSP Model for ISB 2001, a Trispecific T Cell Engager to Support Optimal FIH Study Design in RRMM Patients

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 452-464, August 2026.
ISB 2001 is a trispecific antibody that binds to two tumor‐associated antigens (TAA), CD38 and BCMA, and crosslinks to CD3 on T cells resulting in T cell‐mediated cytotoxicity of tumor cells expressing these TAAs. ISB 2001 is currently being tested in relapsed and/or refractory multiple myeloma (RRMM) patients in the first‐in‐human (FIH) TRIgnite‐1 ...
Vinu Chandralayam Ayyappa Menon   +11 more
wiley   +1 more source

Cattle and bison grazing decreases monarch egg and larval abundance in the Central United States

open access: yesEcosphere, Volume 17, Issue 8, August 2026.
Abstract Monarch butterflies have experienced massive population declines and have been proposed to be listed as threatened under the U.S. Endangered Species Act. Milkweeds (Asclepias spp.) are the sole host plant for monarch larvae, and milkweed abundance has dramatically declined in the past 25 years due to increased usage of herbicides and the ...
Grace Thomas   +4 more
wiley   +1 more source

Medier, offentligheder, køn

open access: yesKvinder, Køn & Forskning, 2014
Michael Nebeling Petersen   +2 more
doaj   +1 more source

Different Yeast Strain Effects on ‘King of the North’ Wine Chemical, Chromatic, and Descriptive Sensory Characteristics

open access: yesFermentation
‘King of the North’ (‘KON’), as a cold-hardy grape, has many advantages, such as tolerance to a wide range of soil conditions and harsh winter climate. Due to the adapting demand of North Dakota’s fruit and wine industry, optimized quality of wine from ...
Zhuoyu Wang   +4 more
doaj   +1 more source

Nutritional adequacy and diet diversity following a tube weaning program

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 2, Page 314-323, August 2026.
Abstract Objectives Limited research has examined nutritional changes following tube weaning. The main objective of this study was to investigate the adequacy and quality of nutrition, growth, and gastrointestinal symptoms in children undergoing a 3‐week outpatient tube weaning program based on hunger provocation.
Maisa Keski‐Kuha   +5 more
wiley   +1 more source

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