Results 71 to 80 of about 3,058 (95)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
A multi‐epitope digital surface‐enhanced Raman spectroscopy framework enables epitope‐resolved immunoprofiling by integrating bispecific antibody fragments with spectrally encoded nanotags. This approach decouples binding events into independent digital channels, allowing structure‐aware antigen analysis.
Jing Wang +4 more
wiley +1 more source
Usynligt? Det professionelle blik på køn og kropslig materialitet i daginstitutioner
The article addresses questions of gender and bodily materiality and how this is included in professional practice in Danish ECEC. Point of departure is the finding that professionals are required to include gender equality and equal opportunities for ...
Jo Krøjer
doaj
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong +6 more
wiley +1 more source
ISB 2001 is a trispecific antibody that binds to two tumor‐associated antigens (TAA), CD38 and BCMA, and crosslinks to CD3 on T cells resulting in T cell‐mediated cytotoxicity of tumor cells expressing these TAAs. ISB 2001 is currently being tested in relapsed and/or refractory multiple myeloma (RRMM) patients in the first‐in‐human (FIH) TRIgnite‐1 ...
Vinu Chandralayam Ayyappa Menon +11 more
wiley +1 more source
Cattle and bison grazing decreases monarch egg and larval abundance in the Central United States
Abstract Monarch butterflies have experienced massive population declines and have been proposed to be listed as threatened under the U.S. Endangered Species Act. Milkweeds (Asclepias spp.) are the sole host plant for monarch larvae, and milkweed abundance has dramatically declined in the past 25 years due to increased usage of herbicides and the ...
Grace Thomas +4 more
wiley +1 more source
‘King of the North’ (‘KON’), as a cold-hardy grape, has many advantages, such as tolerance to a wide range of soil conditions and harsh winter climate. Due to the adapting demand of North Dakota’s fruit and wine industry, optimized quality of wine from ...
Zhuoyu Wang +4 more
doaj +1 more source
Nutritional adequacy and diet diversity following a tube weaning program
Abstract Objectives Limited research has examined nutritional changes following tube weaning. The main objective of this study was to investigate the adequacy and quality of nutrition, growth, and gastrointestinal symptoms in children undergoing a 3‐week outpatient tube weaning program based on hunger provocation.
Maisa Keski‐Kuha +5 more
wiley +1 more source

