Results 91 to 100 of about 28,197 (148)
Splicing Factor Mutations in Clonal Hematopoiesis and Progression to Myeloid Neoplasms
Splicing factor (SF)‐mutant CH is characterized by relatively late emergence and accelerated clonal expansion in older individuals. This review summarizes its clonal dynamics, disease‐associated consequences of SF mutations in myeloid neoplasms, and candidate mechanisms that may contribute to age‐dependent selection.
Yang Lyu, Yutong Zhang, Ayana Kon
wiley +1 more source
ROMATOİD ARTRİTTE EL KEMİK MİNERAL YOĞUNLUĞU VE KEMİK DÖNGÜSÜNÜN BİYOKİMYASAL GÖSTERGELERİ
Amaç: Bu çalışmanın amacı romatoid artritli kadın hastalarda ve sağlıklı kontrollerde el kemik mineral yoğunluk (KMY) ölçümü; osteokalsin ve N-telopeptid (NTX) gibi biyokimyasal göstergelerin değerlendirilmesidir.
Sabire Akın +3 more
doaj
Unraveling the active site cover of coproheme decarboxylase from Listeria monocytogenes
During heme biosynthesis in Gram‐positive bacteria, coproheme decarboxylase (ChdC) catalyzes the conversion of four‐propionate substrate coproheme to the two propionate product heme b. Its active site is universally covered by a flexible linking loop. This study identifies an important histidine residue, which stabilizes the loop in a ChdC homolog.
Nikolaus Falb +4 more
wiley +1 more source
ABSTRACT Knee osteoarthritis (KOA) is a degenerative joint disease primarily driven by the disruption of homeostasis in the chondrocyte extracellular matrix (CECM). This review systematically examines the central role of CECM homeostasis in KOA pathogenesis and summarizes recent advances in this field.
Chao Du +8 more
wiley +1 more source
Renaissance of the Trinitarian: Erwin Schadel's Integral Perspective
Abstract Erwin Schadel (1946–2016), a central yet little‐known figure of the so‐called Bamberg School, developed a distinctive triadic ontology that deserves attention within the contemporary renaissance of Trinitarian thought. Drawing on Augustinian and Comenian sources, Schadel articulates a relational grammar of being through the categories of in ...
Matteo Raffaelli
wiley +1 more source
Correction: The MARC SE-Africa dashboard: Joining forces to counteract emerging antimalarial resistance in South and East Africa. [PDF]
van Wyk S +22 more
europepmc +1 more source
A cell-based kinetic framework enables TCR specificity prediction. [PDF]
Culka M +12 more
europepmc +1 more source
Retention-Based, Dissociation-Sensitive Pre-Screening of Aptamers Using a Centrifugal Microspin Filter. [PDF]
Ahn C, Jeong H, Jeon K, Jung C.
europepmc +1 more source

