Results 101 to 110 of about 4,726,498 (283)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Community Context: Influence and Implications for School Leadership Preparation [PDF]

open access: yes, 2019
Effective K-12 leaders remain a central concern for schools and communities of all types. The purpose of this research is to examine critically the literature on issues facing leaders in rural and urban settings and present a synthesis of cross-cutting ...
Lipke, Tamara, Manaseri, Holly
core   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Lessons in Early Learning: Building an Integrated Pre-K-12 System in Montgomery County Public Schools [PDF]

open access: yes, 2010
Analyzes lessons and strategies from successful efforts to integrate districtwide early learning as part of pre-K-12 school reform, including full-day kindergarten, standards-based curricula, consistency, and parental and community ...
Geoff Marietta
core  

The role of guardians in preventing unintentional injuries among rural children: a mixed-methods study

open access: yesFrontiers in Public Health
BackgroundUnintentional injuries are a leading public health concern for children, particularly in rural areas of low- and middle-income countries.
Liheng Huang   +3 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Limits of Metacognitive Prompts for Confidence Judgments in an Interactive Learning Environment

open access: yesOpen Education Studies
Metacognitive activities are reported to improve learning but prompts to support metacognition have only been investigated with mixed results. In the present study, metacognitive prompts for confidence judgments were implemented in a learning platform to
Klar Maria   +2 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The strongly regular (45,12,3,3) graphs [PDF]

open access: yes, 2006
Using two backtrack algorithms based on dierent techniques, designed and implemented independently, we were able to determine up to isomorphism all strongly regular graphs with parameters v = 45, k = 12, λ = μ = 3.
Coolsaet, K., Degraer, J., Spence, E.
core  

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