Results 71 to 80 of about 672,646 (267)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Hot Carrier Degradation in Si n-MOSFETs at Cryogenic Temperatures

IEEE Journal of the Electron Devices Society
This study experimentally investigated hot carrier degradation (HCD) in Si-MOSFETs at cryogenic temperatures. Stress was applied to the devices at 4 K and 300 K, followed by temperature-dependent characterization from 4 K to 300 K to evaluate the ...
Shunsuke Shitakata, Hiroshi Oka, Kimihiko Kato, Takumi Inaba, Shota Iizuka, Hidehiro Asai, Takahiro Mori   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Probing room temperature indirect and minimum direct band gaps of h-BN

Applied Physics Express
Hexagonal boron nitride (h-BN) has attracted considerable interest as an ultrawide bandgap (UWBG) semiconductor. Experimental studies focused on the detailed near band-edge structure of h-BN at room temperature are still lacking.
N. K. Hossain, A. Tingsuwatit, Z. Alemoush, M. Almohammad, J. Li, J. Y. Lin, H. X. Jiang   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

BUDAYA NOMAD DALAM PERTARUNGAN WACANA MUSIK INDUSTRI INDONESIA STUDI KASUS: BOY-GIRL BAND

Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya, 2019
Boy-girl band K-pop music appearing in Indonesian music industry is a discourse contruction, teritorial or music life style which is brought by pop culture and Korean culture industry.
Dolly Nofer, Titis Srimuda Pitana, Dwi Susanto   +2 more
doaj  

An Improved Performance Radar Sensor for K-Band Automotive Radars. [PDF]

Sensors (Basel), 2023
Abd El-Hameed AS, Ouf EG, Elboushi A, Seliem AG, Izumi Y.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Temporal super-cell engineering and acoustic amplification in dispersive phononic time crystals

Nature Communications
Floquet time crystals, characterized by momentum band gaps (k-gaps), offer powerful mechanisms for exotic wave control. However, selectively harnessing the Floquet band structure and opening multiple k-gaps remains a significant challenge in experiment ...
Ziling Liu, Xinghong Zhu, Zhi-Guo Zhang, Wei-Min Zhang, Xue Chen, Yong-Qiang Yang, Ruwen Peng, Mu Wang, Jensen Li, Hong-Wei Wu   +9 more
doaj   +1 more source