Results 51 to 60 of about 8,415,875 (317)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Instrument uncertainties of network-suitable ground-based microwave radiometers: overview, quantification, and mitigation strategies [PDF]
To enhance observations of the atmospheric boundary layer (ABL), the European Meteorological Network (EUMETNET), and the Aerosol, Clouds, and Trace Gases Research Infrastructure (ACTRIS) are currently collaborating to establish networks of microwave ...
T. Böck +7 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
A miniaturised high‐isolation K‐/Ka‐band diplexer with exceeding adjacent channels using 3D antarafacial channel integration and vertical‐quasi‐coaxial‐based matching network is proposed.
Yujin Zhou +4 more
doaj +1 more source
University Concert Band, University Symphonic Band, November 13, 1980
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan on November 13, 1980, 8:00 p.m., program no.
Western Michigan University. Concert Band
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The Second and Third Data Releases from the UKIRT Hemisphere Survey
This paper describes the second and third data releases (DR2 and DR3, respectively) from the ongoing United Kingdom Infrared Telescope Hemisphere Survey (UHS).
Adam C. Schneider +18 more
doaj +1 more source
University Concert Band, University Symphonic Band, February 17, 1980
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 17, 1980, program no. 205 of the Department of Music's 1979-1980 season.University Concert Band, Gregory Talford, conductor (1st-4th works)
Western Michigan University. Concert Band
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A monolithic K-band MMIC receiver [PDF]
This paper presents the designs and measurement results of a K-band monolithic microwave integrated circuit (MMIC) receiver, including a low noise amplifier and a singly balanced mixer. The MMIC chips are fabricated with a 0.15-/spl mu/m gate-length pseudomorphic (PM) GaAs-based HEMT MMIC technology, carried out by a commercially available foundry.
Wei, Shu-Fen, Lin, I-Hsiang, Wang, Huei
openaire +2 more sources

