Results 91 to 100 of about 17,658,888 (246)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Ultrasonic Echosignal Applied to Human Skin Lesions Characterization

open access: yesArchives of Acoustics, 2013
The paper presents a classification of the healthy skin and the skin lesions (basal cell carcinoma) basing on a statistics of the envelope of ultrasonic echoes. The echoes envelopes distributions were modeled using Rayleigh and K-distribution.
Hanna PIOTRZKOWSKA   +3 more
doaj  

La loi de Pascal restreinte et ses cas particuliers; Constrained Pascal distribution and its special cases [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2012
Pascal distribution, Pa(r, /pi), also called Negative binomial distribution, pertains to the trial number n at which the first r successes have been obtained, each trial being the realization of a Bernoulli variable with success probability /pi.
Louis Laurencelle
doaj  

Generalized distributions of order k associated with success runs in Bernoulli trials

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2003
In a sequence of independent Bernoulli trials, by counting multidimensional lattice paths in order to compute the probability of a first-passage event, we derive and study a generalized negative binomial distribution of order k, type I, which extends to ...
Gregory A. Tripsiannis   +2 more
doaj   +1 more source

Estimation and prediction based on k-record values from normal distribution

open access: yesStatistica, 2014
In this paper, we introduce the k-record values arising from normal distribution. After computing the means, variances and covariances of the k-record values, we determine the best linear unbiased estimators for the location and scale parameters of ...
Manoj Chacko, M. Shy Mary
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Approximating optimally discrete probability distribution with kth-order dependency for combining multiple decisions

open access: yes, 1997
A probabilistic combination of K classifiers' decisions obtained from samples needs a (K + 1)st-order probability distribution. Chow and Liu (1968) as well as Lewis (1959) proposed an approximation scheme of such a high-order distribution with a ...
Kim, JinHyung, Kang, HJ, Kim, K
core  

The architecture of the genome integrates scale independence with inverse symmetry

open access: yesAcademia Molecular Biology and Genomics
The simplest building blocks of the genome, the k-mers, show two properties that are widely observed. Their frequency distribution is scale-free (a variant Zipfian distribution), and the inverse symmetry of k-mers is observable on the same ...
Greg Warr, Les Hatton
doaj   +1 more source

On the conditional distribution of a multivariate Normal given a transformation – the linear case

open access: yesHeliyon, 2019
We show that the orthogonal projection operator onto the range of the adjoint T⁎ of a linear operator T can be represented as UT, where U is an invertible linear operator. Given a Normal random vector Y and a linear operator T, we use this representation
Rajeshwari Majumdar, Suman Majumdar
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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