Results 111 to 120 of about 11,041,440 (317)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

K-centres functional clustering of multivariate functional data

open access: yes, 2016
碩士近年來函數型資料分析逐漸受到重視,而函數型資料之分群分析在實務應用上更是重要的議題。本研究主要是想探討多變量函數型資料的分群問題,當樣本中的每個觀察對象均具有多個變量的函數型資料時,如何找到所有觀測對象的合理分群結構是個尚待解決的問題。本研究將提出一套新的 K 中心多變量函數型分群演算法,其根據 Chiou 與 Li (2007) 對單變量函數型資料所提出的 K 中心函數型分群之概念,利用變量本身的變異程度與不同變量間的相關性來決定各變量適當的權數,並以各變量之加權距離來做分群 ...
郭令証;Kuo, Ling-Cheng
core  

kk k. k. k.k

open access: yes, 1879
in d. Abtheilung für Kriegsgeschichte des K. K.
Kriegsarchiv. Abtheilung für Kriegsgeschichte
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Microglial K(+) channel expression in young adult and aged mice.

open access: yes, 2015
The K(+) channel expression pattern of microglia strongly depends on the cells' microenvironment and has been recognized as a sensitive marker of the cells' functional state. While numerous studies have been performed on microglia in vitro, our knowledge
Tom Schilling   +3 more
core   +1 more source

Engineering Spherically Super-Structured Polyamides for the Sustainable Water Remediation

open access: yesACS Materials Au, 2021
Rajan Kumar   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Imaging of epileptic activity using EEG-correlated functional MRI.

open access: yes, 2005
This thesis describes the method of EEG-correlated fMRI and its application to patients with epilepsy. First, an introduction on MRI and functional imaging methods in the field of epilepsy is provided.
Krakow, K.
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Medicare functional classification levels (K-levels).

open access: yes, 2013
Medicare functional classification levels (K-levels).
Mark V. Albert (323769)   +5 more
core   +1 more source

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