Results 201 to 210 of about 1,851,528 (313)

Functional Comparison of the K+-Cl−Cotransporters KCC1 and KCC4 [PDF]

, 2000
Adriana Mercado, Luyan Song, Norma Vázquez, David B. Mount, Gerardo Gamba   +4 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Unraveling gene interaction networks in colorectal cancer and inflammatory bowel disease via a novel hybrid radial basis function network. [PDF]

Sci Rep
Kırkık D, Bulut F.
europepmc   +1 more source

Convenient on water synthesis of novel derivatives of dicoumarol as functional vitamin K depleter by Fe3O4 magnetic nanoparticles

, 2014
Saeed Khodabakhshi, Bahador Karami, Khalil Eskandari, S. Jafar Hoseini, Hasan Nasrabadi   +4 more
openalex   +1 more source

Tra2α and hnRNP K might be functional partners of Rbm for regulation of RNA processes during spermatogenesis [PDF]

, 2004
Jungmin Lee, Euisu Kim, Sung Key Jang, Kunsoo Rhee   +3 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Plant Diversity and Seasonal Variation Drive Animal Diversity and Community Structure in Eastern China. [PDF]

Animals (Basel)
Chen X, Jiang R, Chen Y, Yang R, He Y, Zou S, Ying J, Yi L, Ye Y, Peng S, Ge Z.   +10 more
europepmc   +1 more source

Molecular analysis of the cryptic and functional phn operons for phosphonate use in Escherichia coli K-12

, 1991
K Makino, Se‐Kwon Kim, Hideo Shinagawa, M Amemura, Akio Nakata   +4 more
openalex   +2 more sources

Molecular Template for a Voltage Sensor in a Novel K+ Channel. III. Functional Reconstitution of a Sensorless Pore Module from a Prokaryotic Kv Channel [PDF]

, 2008
Jose S. Santos, Sergey M. Grigoriev, M Montal   +2 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source