Results 101 to 110 of about 11,198,889 (292)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

RACK: RApid Clustering using K-means algorithm

, 2009
The k-means algorithm is an extremely popular technique for clustering data. One of the major limitations of the k-means is that the time to cluster a given dataset D is linear in the number of clusters, k.
Murty, MN, Garg, Vikas K
core  

K-means algorithm

, 2020
Using K-means algorithm for clustering local regulation in all java region in Indonesia.
Achmad Thoriq, Luh Putu Gayatri Wirastuti, Deanda Bevani Aletha (8517924), nuraini rakhmawati (8517915), Achmad Thoriq (8517918), Deanda Bevani Aletha, Alexander Sidum Laka Kaki (8517927), nuraini rakhmawati, Luh Putu Gayatri Wirastuti (8517921), Alexander Sidum Laka Kaki   +9 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pulse wave time series unsupervised clustering with importance ratios for heart failure subgroups detection

Journal of Biomechanical Science and Engineering
Heart failure (HF) is a significant global public health issue, and accurate diagnosis and effective management are crucial for improving patient outcomes. This study aims to identify potential HF patient subgroups based on the pulse wave time series via
Dandan WU, Ryohei ONO, Sirui WANG, Yoshio KOBAYASHI, Hao LIU   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

K-means distribution map.

, 2016
Map of the distribution of materials and their classification according to the k-means method.
Alfonso Benito-Calvo (559798), Laura Sánchez-Romero (3597266), Alfredo Pérez-González (493352), Manuel Santonja (304484)   +3 more
core   +1 more source

Capacity Optimization Configuration of Hybrid Energy Storage Systems for Wind Farms Based on Improved k-means and Two-Stage Decomposition

Energies
To address the issue of excessive grid-connected power fluctuations in wind farms, this paper proposes a capacity optimization method for a hybrid energy storage system (HESS) based on wind power two-stage decomposition.
Xi Zhang, Longyun Kang, Xuemei Wang, Yangbo Liu, Sheng Huang   +4 more
doaj   +1 more source

A Feature-Reduction Multi-View k-Means Clustering Algorithm

IEEE Access, 2019
The k-means clustering algorithm is the oldest and most known method in cluster analysis. It has been widely studied with various extensions and applied in a variety of substantive areas.
Miin-Shen Yang, Kristina P. Sinaga
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source