Results 111 to 120 of about 2,020,211 (266)
Optimisation of Criminal Data Clustering Model using Information Gain
Crime is a phenomenon that significantly impacts society, necessitating mapping efforts that can be utilized for further analysis. Clustering, as a data analysis technique, groups objects based on similarities or differences in their characteristics ...
Prih Diantono Abda’u +3 more
doaj
Clustering text documents is a fundamental task in modern data analysis, requiring approaches which perform well both in terms of solution quality and computational efficiency.
Kurt Hornik +3 more
doaj
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Due to its simplicity and versatility, k-means remains popular since it was proposed three decades ago. The performance of k-means has been enhanced from different perspectives over the years. Unfortunately, a good trade-off between quality and efficiency is hardly reached. In this paper, a novel k-means variant is presented.
Zhao, Wan-Lei +2 more
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The harvesting of green Sichuan pepper remains heavily reliant on manual field operations, but automation can enhance the efficiency, quality, and sustainability of the process.
Qi Niu +8 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Accelerating the k-Means++ Algorithm by Using Geometric Information
Clustering is a fundamental task in data analysis with applications across a wide range of fields, such as computer vision, pattern recognition, and data mining.
Guillem Rodriguez Corominas +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

