Results 61 to 70 of about 83,604 (260)

Improving Prediction Performance of Dynamic Neighbor Selection in User-Based Collaborative Filtering

Sakarya University Journal of Computer and Information Sciences, 2020
Recommender systems have become more and more popular in online environments in recent years. Although different approaches are introduced to build a powerful recommender system, collaborative filtering is one of the most used approaches in the ...
Burcu Demirelli Okkalıoğlu
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Text intelligent classification model based on improved KNN algorithm in library service transformation

Systems and Soft Computing
With the development of the digital age, library services are facing the challenge of fast and accurate text classification. The traditional K-nearest neighbor algorithm is limited by low classification efficiency and high computational complexity when ...
Changjun Wang, Fengxia You, Yu Wang
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Information Retrieval Document Classified with K-Nearest Neighbor

Record and Library Journal, 2016
Along with the rapid advancement of technology development led to the amount of information available is also increasingly abundant. The aim of this study was to determine how the implementation of information retrieval system in the classification of ...
Badruz Zaman, Endah Purwanti, Alifian Sukma   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

K-Nearest Neighbor and Weight K-Nearest Neighbor Classification of Cork Fish Using Gray-Level-Co-Occurrence Matrix Algorithm Approach

JOIV: International Journal on Informatics Visualization
Ornamental cork fish is a type of fish that is in great demand among the public as an ornamental fish. Ornamental cork fish have various types and colors; each variation has its own name and is a selling point among ornamental cork fish lovers.
Euis Nur Fitriani Dewi, Andi Nur Rachman, Rahmi Nur Shofa, Genta Nazwar Tarempa   +3 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Information Retrieval Document Classified with K-Nearest Neighbor

Record and Library Journal, 2018
Along with the rapid advancement of technology development led to the amount of information available is also increasingly abundant. The aim of this study was to determine how the implementation of information retrieval system in the classification of ...
Alifian Sukma, Badruz Zaman, Endah Purwanti   +2 more
doaj   +1 more source