Results 41 to 50 of about 312,403 (279)

k-nearest neighbors prediction and classification for spatial data

, 2018
We propose a nonparametric predictor and a supervised classification based on the regression function estimate of a spatial real variable using k-nearest neighbors method (k-NN). Under some assumptions, we establish almost complete or sure convergence of
Ahmed, Mohamed-Salem, Attouch, Mohammed Kadi, Dabo-Niang, Sophie, N'diaye, Mamadou   +3 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Adaptive K values and training subsets selection for optimal K-NN performance on FPGA

Journal of King Saud University: Computer and Information Sciences
This study introduces an Adaptive K-Nearest Neighbors methodology designed for FPGA platforms, offering substantial improvements over traditional K-Nearest Neighbors implementations.
Achraf El Bouazzaoui, Noura Jariri, Omar Mouhib, Abdelkader Hadjoudja   +3 more
doaj   +1 more source

Spiral ground state in the quasi-two-dimensional spin-1/2 system Cu2GeO4

, 2011
We apply density functional theory band structure calculations, the coupled-cluster method, and exact diagonalization to investigate the microscopic magnetic model of the spin-1/2 compound Cu2GeO4.
Richter, Johannes, Rosner, Helge, Tsirlin, Alexander A., Zinke, Ronald   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Two-spin subsystem entanglement in spin 1/2 rings with long range interactions

, 2007
We consider the two-spin subsystem entanglement for eigenstates of the Hamiltonian \[ H= \sum_{1\leq j< k \leq N} (\frac{1}{r_{j,k}})^{\alpha} {\mathbf \sigma}_j\cdot {\mathbf \sigma}_k \] for a ring of $N$ spins 1/2 with asssociated spin vector ...
G. A. Raggio, M. Gaudiano, O. Osenda, S. Sachdev, T. Kato   +4 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A Classifier Based on K-Nearest Neighbors Using Weighted Summation of Reconstruction Errors [PDF]

مجله مدل سازی در مهندسی
In this paper, a classifier is introduced based on the nearest neighbor classifier and the reconstruction error for data classification. In the proposed method, first, K nearest data points (neighbors) from each category in the training data are ...
Rassoul Hajizadeh, Mohammad Ali Hosseinzadeh   +1 more
doaj   +1 more source

Optimasi Parameter K Pada Algoritma K-NN Untuk Klasifikasi Prioritas Bantuan Pembangunan Desa

Techno.Com, 2021
Klasifikasi adalah proses menemukan model atau fungsi yang menggambarkan dan membedakan kelas atau konsep data. Algoritma k-NN (k Nearest Neighbors) merupakan algoritma klasifikasi berdasarkan pembelajaran dari data yang sudah terklasifiasi sebelumnya ...
Saiful Ulya, M Arief Soeleman, Fikri Budiman   +2 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source