Results 41 to 50 of about 169,777 (262)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

K2-237 b and K2-238 b: Discovery and characterization of two new transiting hot Jupiters from K2 [PDF]

, 2018
We report the discovery of two hot Jupiters orbiting the stars K2-237 and K2-238. We used photometric data from Campaigns 11 and 12 of the Kepler K2 mission and radial velocity data obtained using the HARPS, FEROS, and CORALIE spectrographs. K2-237 b and
Vučković, M., Espinoza, N., F Rojas, Jenkins, J., A Jordán, Díaz, M., Lachaume, R., E Gonzales, Pantoja, B., Soto, M., R Lachaume, Jones, M., B Pantoja, M Vučković, R Brahm, I Crossfield, Jenkins, James Stewart, Hartman, J., L Hirsch, Dressing, C., Gonzales, E., N Espinoza, D R Ciardi, Crossfield, I., C Dressing, Rojas, F., M I Jones, M Rabus, Hirsch, L., H Drass, Brahm, R., Jordán, A., J S Jenkins, P Sarkis, Rabus, M., Sarkis, P., M G Soto, M R Díaz, J Hartman, Ciardi, D., Drass, H., Brahm Scott, Rafael, Drass, H, Crossfield, Ian Jm, Gonzales, E, Díaz, M.R., Pantoja, B, Rabus, Markus, Espinoza, N, Jordán, A, Lachaume, R, Hartman, J, Sarkis, P, Rojas, F, Jones, MI, Vučković, M, Jenkins, J.S., Crossfield, I, Jones Fernández, Matías Ignacio, Rabus, M, Ciardi, DR, Rojas Aracena, Felipe Alberto., Soto, M.G., Hartman, JD., Drass, Holger, Brahm, R, Hirsch, L, Lachaume, Regis, Jenkins, JS, Dressing, C, Soto, MG, Díaz, MR   +71 more
core   +2 more sources

High-precision photometry for K2 Campaign 1 [PDF]

, 2015
The two reaction wheel K2 mission promises and has delivered new discoveries in the stellar and exoplanet fields. However, due to the loss of accurate pointing, it also brings new challenges for the data reduction processes.
Domsa, I, Penev, K, Bakos, G. A., Huang, C. X., Huang, CX, Hartman, Joel D., de Val-Borro, M., de Val-Borro, Miguel, Penev, K., Bhatti, W, Bhatti, W., Domsa, I., Bakos, Gaspar Aron, Hartman, J. D.   +13 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

A Modular Synthetic Demand Generation Framework for Demand-Responsive Public Transport

IEEE Open Journal of Intelligent Transportation Systems
This study develops a modular framework for generating synthetic demand for demand-responsive public transport (DRT) using real service data. From 518 days of operational records (~37,000 trips), we construct a simulated empirical demand (SED) baseline ...
Shairyar Malik, Jan A. Persson, Ase Jevinger   +2 more
doaj   +1 more source

Crystal structure of dimethylformamidium bis(trifluoromethanesulfonyl)amide: an ionic liquid

Acta Crystallographica Section E: Crystallographic Communications, 2016
At 100 K, the title molecular salt, C3H8NO+·C2F6NO4S2−, has orthorhombic (P212121) symmetry; the amino H atom of bis(trifluoromethanesulfonyl)amine (HNTf2) was transferred to the basic O atom of dimethylformamide (DMF) when the ionic liquid components ...
Allan Jay P. Cardenas, Molly O'Hagan
doaj   +1 more source

Chitin‐Derived Carbon‐Metal Functional Materials

Advanced Functional Materials, EarlyView.
Functional carbon materials are synthesized from combination of biopolymer (chitin) and iron precursors. The resultant material exhibits superior surface area and adsorptive properties compared to carbon materials synthesized directly from pure chitin.
Herry Fang, Chao Hsuan (Joseph) Sung, Haitao Yu, Ezra Sarmiento, Katarina Kotanchek, Ryan Christopher Lee, Michelle Chan, David Kisailus   +7 more
wiley   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Drop‐on‐Demand Printed Negative Dielectric Anisotropy Liquid Crystal Droplets for Adaptive Complex Beam Manipulation and Assessment

Advanced Functional Materials, EarlyView.
Printed negative‐dielectric‐anisotropy liquid‐crystal droplets enable multidimensional full‐vectorial optical‐field sensing across polarization, phase, and wavelength, while also generating tunable skyrmionic‐like complex optical fields. ABSTRACT Adaptive manipulation of vectorial optical fields is important for optical metrology, imaging, and ...
Jinge Guo, Xuke Qiu, Runchen Zhang, Qihao Han, Liangyu Deng, Yishun Lu, Zimo Zhao, Mengmeng Li, Waqas Kamal, Junseok Ma, Yongge Ma, Steve J. Elston, Alfonso A. Castrejón‐Pita, Stephen M. Morris, Chao He   +14 more
wiley   +1 more source