Results 51 to 60 of about 1,630 (169)

Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

open access: yeseLife, 2022
Phosphorylation and acetylation of sarcomeric proteins are important for fine-tuning myocardial contractility. Here, we used bottom-up proteomics and label-free quantification to identify novel post-translational modifications (PTMs) on β-myosin heavy ...
Maicon Landim-Vieira   +14 more
doaj   +1 more source

Genetic code expansion and enzymatic modifications as accessible methods for studying site‐specific post‐translational modifications of alpha‐synuclein and tau

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract Alpha‐synuclein (αS) and tau play important roles in the pathology of Parkinson's disease and Alzheimer's disease, respectively, as well as numerous other neurodegenerative diseases. Both proteins are classified as intrinsically disordered proteins (IDPs), as they have no stable structure that underlies their function in healthy tissue, and ...
Ibrahim G. Saleh   +17 more
wiley   +1 more source

Crystal structure and biophysical characterisation of the enterococcal foldase PpiC, a cross‐opsonic antigen against gram‐positive nosocomial pathogens

open access: yesThe FEBS Journal, Volume 292, Issue 20, Page 5475-5490, October 2025.
PpiC is an enterococcal lipoprotein endowed with both Peptidyl‐prolyl cis‐trans isomerase (PPIase) and foldase activities. It is a potential target for novel antimicrobials and a promising vaccine antigen. We determined the crystal structure of the enzyme, showing that PpiC adopts a dimeric organisation embedding two catalytic parvulin‐type PPIase ...
Valeria Napolitano   +7 more
wiley   +1 more source

The Theory of Planned Behaviour as a Research Tool an Connection with Tax Law and Economics

open access: yesFinancial Law Review, 2021
The Theory of Planned Behaviour (TPB) is a theory from the field of psychology that was developed by Icek Ajzen in 1985 in order to predict and change human behavior. The theory works with three basic
Jana Bellová, Taťána Špírková
doaj   +1 more source

Effect of a ceruminolytic ear cleaner on clinical, microbiological and ear canal microbiome evolution in canine erythemato‐ceruminous otitis externa associated with proliferation of Malassezia yeasts

open access: yesVeterinary Dermatology, Volume 36, Issue 5, Page 668-678, October 2025.
Background – Erythemato‐ceruminous otitis externa (ECOE) is commonly associated with Malassezia spp. and microbial imbalance. Hypothesis/Objective – To assess the clinical performance of an ear cleaner in dogs suffering from ECOE associated with Malassezia spp. overgrowth and to measure its impact on the microbiota. Conclusions and Clinical Relevance –
Amaury Briand   +11 more
wiley   +1 more source

The Taxpayer’s Right to Privacy in Context of the Article 48 of the Polish Act on National Revenue Administration (KAS)

open access: yesFinancial Law Review, 2023
The considerations concern a problem that is rarely raised on the basis of tax issues, namely the taxpayer's right to privacy. They are carried out in the context of one of the legal regulations which
Anna Drywa
doaj   +1 more source

On Combining Conventional Point‐To‐Point and Automated Waste Collection Systems

open access: yesNetworks, Volume 86, Issue 2, Page 174-198, September 2025.
ABSTRACT The global demand for sustainable waste management has spurred initiatives to improve the efficiency of urban waste collection, discussing the advantages and disadvantages of different systems. We analyze a new combined waste collection problem that uses two systems simultaneously: a point‐to‐point system, in which waste is collected using ...
Maryam DehghanChenary   +3 more
wiley   +1 more source

Mutu Sap Liquid Rumput Laut Sargassum yang Diekstrak Menggunakan Kalium Hidroksida sebagai Bahan Pupuk

open access: yesJurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2015
Penelitian ekstraksi sap dari rumput laut Sargassum telah dilakukan dengan menggunakan larutan KOH. Sebelum dilakukan perlakuan Sargassum direndam dalam HCl 1% selama 2 jam, dicuci dengan air tawar dan ditiriskan.
Jamal Basmal   +2 more
doaj   +1 more source

Regulatory impact assessments (Ria) As an input in tax law interpretation: Analysis of the administrative courts verdicts

open access: yesFinancial Law Review, 2022
The goal of this paper is to empirically examine the role of Regulatory Impact Assessments (RIAs) accompanying draft laws submitted by the Council of the Ministers as an input in purpose-oriented ...
Dominik Gajewski, Kamil Joński
doaj   +1 more source

Thermotolerant class A acid phosphatase active across broad pH range and diverse substrates

open access: yesProtein Science, Volume 34, Issue 9, September 2025.
Abstract M2‐32 is a non‐specific acid phosphatase with a rare ability to function across a broad pH range (3.5–8.5). Analysis using SWISS‐PROT Prf Profiles classifies it as a class A acid phosphatase (Z‐score: 78.97), sharing 50%–60% sequence similarity with enzymes such as PhoC and PhoN.
Maria‐Isabel Recio   +7 more
wiley   +1 more source

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