Results 61 to 70 of about 1,630 (169)

PRMT1‐Mediated SWI/SNF Complex Recruitment via SMARCC1 Drives IGF2BP2 Transcription to Enhance Carboplatin Resistance in Head and Neck Squamous Cell Carcinoma

Advanced Science, Volume 12, Issue 22, June 12, 2025.
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu, Wentao Zhang, Weiwei Liu, Zhao Ding, Ruijing Zhang, Yuefeng Han, Zihao Niu, Mengdie Zhang, Hui Li, Dapeng Li, Zixi Wang, Jie Peng, Yu Wu, Yanxun Han, Zihui Xie, Jing Wu, Liang Qin, Zhongdong Hu, Xu Chen, Yunlong Hu, Yehai Liu, Shiyin Ma, Xiaojun Zha   +22 more
wiley   +1 more source

Inter-scallop separations of the posterior leaflet of the mitral valve: an important cause of ‘pathological’ mitral regurgitation in rheumatic heart disease screening

Echo Research and Practice, 2018
The 2012 World Heart Federation (WHF) criteria for echocardiographic diagnosis of rheumatic heart disease (RHD) identify that the finding of ‘pathological’ mitral regurgitation (MR) in a screened individual increases the likelihood of detecting ...
L D Hunter, M Monaghan, G Lloyd , A J K Pecoraro, A F Doubell, P G Herbst   +5 more
doaj   +1 more source

Seasonal Influence on Subsurface Rates of Microbial Sulfate Reduction and Sulfur Isotope Fractionation in Coastal Sediments

Global Biogeochemical Cycles, Volume 39, Issue 6, June 2025.
Abstract Sulfur isotope fractionation during microbial sulfate reduction is often preserved in the mineral pyrite (FeS2), which has been used to reconstruct the biogeochemical sulfur cycle and redox geochemistry of the oceans over the Earth history.
Bizhou Zhu, Harold J. Bradbury, Thomas I. Marquand, Angus Fotherby, Caroline M. Daunt, Josephine A. Clegg, Beth Williams, Jonathan D. Todd, Michael J. Bickle, Fiona Llewellyn‐Beard, Alexandra V. Turchyn   +10 more
wiley   +1 more source

Mutu Sap Liquid Rumput Laut Sargassum yang Diekstrak Menggunakan Kalium Hidroksida sebagai Bahan Pupuk

Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 2016
Penelitian ekstraksi sap dari rumput laut Sargassum telah dilakukan dengan menggunakan larutan KOH. Sebelum dilakukan perlakuan Sargassum direndam dalam HCl 1% selama 2 jam, dicuci dengan air tawar dan ditiriskan.
Jamal Basmal, Rinta Kusumawati, Bagus Sediadi Bandol Utomo   +2 more
doaj   +1 more source

Rainfall seasonality shapes belowground root trait dynamics in an Amazonian tropical rainforest: A test of the stress‐dominance hypothesis

Functional Ecology, Volume 39, Issue 3, Page 799-812, March 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The stress‐dominance hypothesis (SDH) predicts that trait variation at the community level increases with the availability of limiting resources, driving spatial and temporal patterns in above‐ground plant functional trait expression.
Oscar J. Valverde‐Barrantes, Laynara F. Lugli, Lucia Fuchslueger, Florian Hofhansl, Nathielly Martins, Amanda L. Cordeiro, Karst Schapp, Kelly M. Anderson, Sabrina Garcia, Adriana Grandis, Carol A. Miron, Katrin Fleisher, Marcel R. Hoosbeek, Ian P. Hartley, Erick Oblitas Mendoza, David Lapola, Carlos A. Quesada   +16 more
wiley   +1 more source

Protective Effects of Oridonin on Acute Liver Injury via Impeding Posttranslational Modifications of Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) in the Toll-Like Receptor 4 (TLR4) Signaling Pathway

Mediators of Inflammation, 2019
Objective. Recent researches have demonstrated that inflammation-related diseases are effectively regulated by posttranslational modifications (PTMs) including phosphorylation and acetylation.
Min Shi, Yilin Deng, Heguo Yu, Ling Xu, Cuicui Shi, Jiong Chen, Guangming Li, Yiqi Du, Yu-gang Wang   +8 more
doaj   +1 more source

Modeling radiative transfer in tropical rainforest canopies: sensitivity of simulated albedo to canopy architectural and optical parameters

Anais da Academia Brasileira de Ciências, 2011
This study evaluates the sensitivity of the surface albedo simulated by the Integrated Biosphere Simulator (IBIS) to a set of Amazonian tropical rainforest canopy architectural and optical parameters.
Sílvia N. M. Yanagi, Marcos H. Costa
doaj   +1 more source

Ubiquitin‐specific protease 25 improves myocardial ischemia–reperfusion injury by deubiquitinating NLRP3 and negatively regulating NLRP3 inflammasome activity in cardiomyocytes

Clinical and Translational Medicine, Volume 15, Issue 2, February 2025.
Abstract Background Myocardial ischemia/reperfusion injury (MI/RI) restricts the effect of myocardial reperfusion therapy and lacks effective prevention and treatment methods. Deubiquitinating enzymes (DUBs), especially members of the ubiquitin‐specific protease (USP) family of DUBs, are key proteins in the ubiquitination modification process and play
Bozhi Ye, Diyun Xu, Lingfeng Zhong, Yi Wang, Wei Wang, Haowen Xu, Xue Han, Julian Min, Gaojun Wu, Wenhai Huang, Guang Liang   +10 more
wiley   +1 more source

Filter Design Using Ultra‐Miniaturised Substrate‐Integrated Coaxial Cavity

IET Microwaves, Antennas &Propagation, Volume 19, Issue 1, January/December 2025.
The proposed substrate‐integrated coaxial cavity (SICC) comprises two dielectric substrates with three metal layers. The top and bottom metal layers form the cavity's broadside walls, and the middle is a circular patch that shorts to the bottom wall and to an embedded split CPW ring, respectively, through a blind‐via ring and three blind vias.
Min‐Hua Ho, Chun‐Ming Hung, Chung‐I G. Hsu   +2 more
wiley   +1 more source

Post‐translational modifications of proteins in cardiovascular diseases examined by proteomic approaches

The FEBS Journal, Volume 292, Issue 1, Page 28-46, January 2025.
Mass spectrometry (MS)‐based proteomics has proven to be a powerful method capable of mapping, localizing and quantifying post‐translational modifications (PTMs). PTMs play regulatory roles in protein functions/activities and the recognition of PTMs specific to cardiovascular pathologies is crucial for usage in clinics.
Miroslava Stastna
wiley   +1 more source