Results 111 to 120 of about 6,975 (268)

Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea [PDF]

, 2006
Gap junctional intercellular communication (GJIC) plays a major role in cochlear function. Recent evidence suggests that connexin 26 (Cx26) and Cx30 are the major constituent proteins of cochlear gap junction channels, possibly in a unique heteromeric ...
Forge, A, Jagger, DJ
core   +1 more source

[Pathophysiological aspects of K+: Cl- cotransporters].

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 2014
The K+:Cl- cotransporters or KCCs are membrane proteins that move K+ and Cl- ions across the membrane without changing the transmembrane potential. KCCs belong to the SLC12 (Solute Carrier Family 12) family of electroneutral cation-chloride cotransporters (CCC), and they are secondary active ion transporters because use the established gradients from ...
Adriana, Mercado, Zesergio, Melo
openaire   +1 more source

Spreading depolarization and its influence on epileptiform activity

Epilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque, Rüdiger Köhling, Massimo Avoli   +2 more
wiley   +1 more source

The essential roles of metal ions in insect homeostasis and physiology [PDF]

, 2017
Metal ions play distinct roles in living organisms, including insects. Some, like sodium and potassium, are central players in osmoregulation and ‘blood and guts’ transport physiology, and have been implicated in cold adaptation.
Dow, Julian A.T.
core   +1 more source

Expression of corticoid‐regulatory genes in the gills of Atlantic salmon (Salmo salar) parr and smolt and during salinity acclimation

Journal of Fish Biology, EarlyView.
Abstract In teleost fishes, cortisol is the major corticoid and has both glucocorticoid and mineralocorticoid actions. However, how fish tissues discriminate between these distinct corticosteroid actions is unclear. In mammals, the major factors responsible for intracellular corticosteroid regulation are glucocorticoid receptors (grs) and the ...
Makoto Kusakabe, Takashi Yada, Graham Young, Amy M. Regish, Stephen D. McCormick   +4 more
wiley   +1 more source

Renal phosphaturia during metabolic acidosis revisited: molecular mechanisms for decreased renal phosphate reabsorption [PDF]

, 2018
During metabolic acidosis (MA), urinary phosphate excretion increases and contributes to acid removal. Two Na+-dependent phosphate transporters, NaPi-IIa (Slc34a1) and NaPi-IIc (Slc34a3), are located in the brush border membrane (BBM) of the proximal ...
Biber, Jürg, Capuano, Paola, Murer, Heini, Nowik, Marta, Picard, Nicolas, Stange, Gerti, Tenenhouse, Harriet, Wagner, Carsten   +7 more
core  

Functional kinomics establishes a critical node of volume-sensitive cation-Cl^- cotransporter regulation in the mammalian brain [PDF]

, 2016
This is the final version of the article. Available from the publisher via the DOI in this record.There is another record in ORE for this publication: http://hdl.handle.net/10871/33424Cell volume homeostasis requires the dynamically regulated transport ...
A Birmingham, A ElAli, A Madeira, A Roy, AA Altamirano, AC Vitari, AL Jackson, AM Ring, AV Sarthy, B Lenart, BD Manning, BE Xu, BF Dowd, BM Filippi, C Lytle, EK Hoffmann, F Hong, F Lang, FK Voss, G Begum, G Su, G Su, H Zhang, HY Wu, J Brillault, J Rinehart, J Zhang, JA Stokum, JM Simard, JO Thastrup, JV Olsen, K Piechotta, K Piechotta, K Pollizzi, K Strange, K Strange, KT Kahle, KT Kahle, L Cong, L Erokhova, M Amiry-Moghaddam, M Haas, M Zheng, MA Lawlor, MB Rust, ME O’Donnell, ME O’Donnell, ML Jennings, ML Jennings, N Manhas, NC Adragna, NC Adragna, NJ Abbott, P de Los Heros, PB Dunham, PS Lee, R Planells-Cases, R Syeda, RB Darman, S Heidari Nejad, S Michinaga, S Morgan-Lappe, SE Morgan-Lappe, SF Pedersen, SK Tahir, T Boettger, T Kuroiwa, T Mori, T Moriguchi, TJ Jentsch, Wallace F Marshall, X Lin, Y Durocher   +72 more
core   +3 more sources

Salt glands in exo‐recretohalophytes: Development, physiological functions, and prospects for improving crop salt tolerance

Journal of Integrative Plant Biology, EarlyView.
This review examines salt glands in exo‐recretohalophytes, in which epidermal stem cells differentiate into unicellular, bicellular, or multicellular salt glands. Salt ions are transported to the leaves via the transpiration stream and enter salt glands through symplastic and apoplastic pathways. Finally, salt glands actively secrete salt ions from the
Limin Wang, Junyan Xie, Yiping Zou, Chunliang Yao, Hai Fan, Chenqi Shen, Wenyan Zhou, Jingran Qin, Xinke Zhang, Baoshan Wang, Jian Zhang, Guoliang Han   +11 more
wiley   +1 more source

Functionally Important Residues in the Predicted 3rd Transmembrane Domain of the Type IIa Sodium-phosphate Cotransporter (NaPi-IIa) [PDF]

, 2018
The type IIa Na+/Pi, cotransporter (NaPi-IIa) mediates electrogenic transport of three Na+ and one divalent Pi ion (and one net positive charge) across the cell membrane.
Bacconi, A., Biber, J., Forster, I.C., Murer, H., Virkki, L.V.   +4 more
core  

Na/K/Cl cotransport in cultured human fibroblasts.

Journal of Biological Chemistry, 1985
The transport characteristics and regulation of the Na/K/Cl cotransport system were investigated in cultured human fibroblasts (HSWP cells). The existence of the system was documented by the finding that digitoxin-insensitive K+ influx was dependent upon the presence of both Na+ and Cl- in the extracellular milieu.
N E, Owen, M L, Prastein
openaire   +2 more sources