Results 161 to 170 of about 3,400 (190)
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Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: modulation by cytoplasmic Cl
American Journal of Physiology-Cell Physiology, 1996The effect of cytoplasmic Cl concentration ([Cl]i) on the activation state ([3H]benzmetanide binding rate) and phosphorylation state (32P incorporation) of the Na-K-Cl cotransporter was evaluated in secretory tubules isolated from the dogfish shark rectal gland.
C, Lytle, B, Forbush
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American Journal of Physiology-Cell Physiology, 1995
The Na-K-Cl cotransport system of vascular endothelial cells plays a central role in maintenance and regulation of intracellular volume. Activity of the cotransporter is modulated both by hormones and by extracellular tonicity. Vasopressin and other hormones that stimulate the endothelial cotransporter act via a Ca- and calmodulin-dependent pathway ...
M E, O'Donnell, A, Martinez, D, Sun
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The Na-K-Cl cotransport system of vascular endothelial cells plays a central role in maintenance and regulation of intracellular volume. Activity of the cotransporter is modulated both by hormones and by extracellular tonicity. Vasopressin and other hormones that stimulate the endothelial cotransporter act via a Ca- and calmodulin-dependent pathway ...
M E, O'Donnell, A, Martinez, D, Sun
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The Role of K+-Cl−-Cotransporter-2 in Neuropathic Pain
Neurochemical Research, 2018The pain sensory system normally functions under a fine balance between excitation and inhibition. When this balance is perturbed for some reason, it leads to neuropathic pain. There is accumulating evidence that attributes this pain generation to specific dysfunctions of the inhibitory system in the spinal cord.
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Characteristics and functions of Na-K-Cl cotransport in epithelial tissues
American Journal of Physiology-Cell Physiology, 1987This review summarizes our present understanding of Na-K-Cl cotransport and its physiological role in absorption and secretion of electrolytes and water in epithelial tissues. In the past several years an extensive literature about this cotransporter has developed due to its widespread distribution in a variety of cell types and its essential role in ...
S M, O'Grady, H C, Palfrey, M, Field
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K+-Cl- Cotransport in Vertebrate Red Cells
2003The “pump-leak” model of Tosteson and Hoffman (1960) presented an elegant and simple paradigm for regulation of red blood cell (RBC) cation content and volume. It emphasised the importance of a specific, ouabain-sensitive, Na+/K+ pump, driven by ATP, as the primary active transport process for maintaining high intracellular K+, balancing K+ loss ...
John S. Gibson, J. Clive Ellory
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Molecular Properties of the Na-K-Cl-Cotransporter
1991Since 1980, when the transporter was first characterized in Ehrlich Ascites tumor cells [1], the Na-K-Cl cotransport system has been found to play a major role in volume regulation in cells in general, and in transepithelial active chloride transport in epithelia in particular [2].
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[Na+/K+/2Cl- cotransport protein, Na+/Cl- cotransport protein].
Nihon rinsho. Japanese journal of clinical medicine, 1997The bumetanide-sensitive Na+/K+/2Cl- cotransporter and the thiazide-sensitive Na+/Cl- cotransporter are present in a wide variety of tissues, and appear to serve physiological cell functions such as volume control, particularly the phenomenon known as regulatory volume control, and net secretion or absorption of salt.
T, Inoue, H, Nonoguchi, K, Tomita
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The Na‐K‐Cl Cotransporter in the Kidneya
Annals of the New York Academy of Sciences, 1989openaire +2 more sources