Results 251 to 260 of about 6,975 (268)

Role of Na/K/Cl cotransport in astrocytes

Canadian Journal of Physiology and Pharmacology, 1992
The kinetic characterization of the Na/K/Cl cotransport of cultured astrocytes and evidence for its involvement in volume regulation and K+ net uptake during K+ clearance are reviewed. Emphasis is put on experimental evidence for a proposed sodium cycle in astrocytes; this cycle involves a Na+–K+ ATPase that is stimulated by both a high external K ...
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Na‐K‐Cl Cotransport in Chloride‐transporting Epithelia^a

Annals of the New York Academy of Sciences, 1985
The elasmobranch rectal gland has served as a useful model to study features of Na-K-Cl cotransport that are common to many chloride-transporting epithelia. These include: (1) dependence on a Na+ gradient created by Na-K-ATPase; (2) high intracellular Cl- concentration; (3) characteristic inhibitor profile including inhibition by loop diuretics and ...
F H, Epstein, P, Silva
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[Na+/K+/2Cl- cotransport protein, Na+/Cl- cotransport protein].

Nihon rinsho. Japanese journal of clinical medicine, 1997
The bumetanide-sensitive Na+/K+/2Cl- cotransporter and the thiazide-sensitive Na+/Cl- cotransporter are present in a wide variety of tissues, and appear to serve physiological cell functions such as volume control, particularly the phenomenon known as regulatory volume control, and net secretion or absorption of salt.
T, Inoue, H, Nonoguchi, K, Tomita
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K+-Cl- Cotransport in Vertebrate Red Cells

2003
The “pump-leak” model of Tosteson and Hoffman (1960) presented an elegant and simple paradigm for regulation of red blood cell (RBC) cation content and volume. It emphasised the importance of a specific, ouabain-sensitive, Na+/K+ pump, driven by ATP, as the primary active transport process for maintaining high intracellular K+, balancing K+ loss ...
John S. Gibson, J. Clive Ellory
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PEROXYNITRITE ACTIVATES K⁺‐Cl⁻COTRANSPORT IN HUMAN ERYTHROCYTES

Cell Biology International, 2001
Peroxynitrite was found to induce the release of K+ via the Na+/Cl− cotransport system, as do other oxidants. Since peroxynitrite is formed in vivo, its presence could contribute to a pathological dehydration of red blood cells.
A, Grzelak, J, Mazur, G, Bartosz
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Intracellular Cl regulates Na-K-Cl cotransport activity in human trabecular meshwork cells

American Journal of Physiology-Cell Physiology, 1999
The trabecular meshwork (TM) of the eye plays a central role in modulating intraocular pressure by regulating aqueous humor outflow, although the mechanisms are largely unknown. We and others have shown previously that aqueous humor outflow facility is modulated by conditions that alter TM cell volume.
L K, Putney, C R, Vibat, M E, O'Donnell
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Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: modulation by cytoplasmic Cl

American Journal of Physiology-Cell Physiology, 1996
The effect of cytoplasmic Cl concentration ([Cl]i) on the activation state ([3H]benzmetanide binding rate) and phosphorylation state (32P incorporation) of the Na-K-Cl cotransporter was evaluated in secretory tubules isolated from the dogfish shark rectal gland.
C, Lytle, B, Forbush
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Molecular characterization of the epithelial NaKCl cotransporter isoforms

Current Opinion in Cell Biology, 1995
Recent advances in the molecular characterization of specific isoforms of the Na-K-Cl cotransporter have allowed rapid progress in the study of the structure, function, and regulation of these members of a family of Cl-dependent cation cotransporters.
J A, Payne, B, Forbush
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Molecular Properties of the Na-K-Cl-Cotransporter

1991
Since 1980, when the transporter was first characterized in Ehrlich Ascites tumor cells [1], the Na-K-Cl cotransport system has been found to play a major role in volume regulation in cells in general, and in transepithelial active chloride transport in epithelia in particular [2].
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Pathophysiology of the K+-Cl− Cotransporters

2010
John S. Gibson, J. Clive Ellory, Norma C. Adragna, Peter K. Lauf   +3 more
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