Results 111 to 120 of about 20,244,257 (338)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A probabilistic combination of K classifiers' decisions obtained from samples needs a (K + 1)st-order probability distribution. Chow and Liu (1968) as well as Lewis (1959) proposed an approximation scheme of such a high-order distribution with a ...
Kim, JinHyung, Kang, HJ, Kim, K
core
The K value as a freshness index for tropical food fish and its application as a quality control tool during fish storage and distribution [PDF]
The K value, expressed as K value % = HxR + Hx /ATP + ADP + AMP + IMP + HxR + Hx x 100 is a good index for estimating the enzymatic freshness of fish. The changes in K value of various species of tropical food fishes during ice-storage had been studied ...
Ng, Cher Siang, Tan-Teo, Poh Hong
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Thermal energy storage contribution to the economic dispatch of island power systems
Panagiotis Romanos +3 more
doaj +1 more source
On a type of almost Kenmotsu manifolds with nullity distributions
The object of the present paper is to characterize Weyl semisymmetric almost Kenmotsu manifolds with its characteristic vector field ξ belonging to the (k,μ)′-nullity distribution and (k,μ)-nullity distribution respectively.
U.C. De, Krishanu Mandal
doaj +1 more source
Contact manifolds, harmonic curvature tensor and $(k,\mu )$-nullity distribution [PDF]
summary:In this paper we give first a classification of contact Riemannian manifolds with harmonic curvature tensor under the condition that the characteristic vector field $\xi $ belongs to the $(k,\mu )$-nullity distribution.
Papantoniou, Basil J.
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

