Results 91 to 100 of about 9,360,077 (298)

A generalized k-nearest neighbor rule

open access: yesInformation and Control, 1970
A family of supervised, nonparametric decision rules, based on tolerance regions, is described which includes the k-Nearest Neighbor decision rules when there are two classes. There are two practical reasons for doing so: first, a family of decision rules similar to the k-Nearest Neighbor rules can be specified which applies to a broader collection of ...
Edward A. Patrick   +1 more
openaire   +2 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

yaImpute: An R Package for kNN Imputation [PDF]

open access: yes
This article introduces yaImpute, an R package for nearest neighbor search and imputation. Although nearest neighbor imputation is used in a host of disciplines, the methods implemented in the yaImpute package are tailored to imputation-based forest ...
Andrew O. Finley, Nicholas L. Crookston
core  

Taxonomic classification of genomic sequences : from whole genomes to environmental genomic fragments [PDF]

open access: yes, 2010
Díaz Solórzano NN. Taxonomic classification of genomic sequences : from whole genomes to environmental genomic fragments. Bielefeld (Germany): Bielefeld University; 2010.The main goal of this dissertation is to develop a classifier for assigning ...
Díaz Solórzano, Naryttza Namelly
core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Application of Data Mining for Tuberculosis Disease Classification Using K-Nearest Neighbor

open access: yesJurnal Sisfokom
This study aims to find out how much the application of the K-NN method and the accuracy value obtained by the K-NN method in clarifying data of Tuberculosis patients. This research focuses on improving public health and developing science to help people
Delima Sitanggang   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Bias in nearest-neighbor hazard estimation [PDF]

open access: yes
In nonparametric curve estimation, the smoothing parameter is critical for performance. In order to estimate the hazard rate, we compare nearest neighbor selectors that minimize the quadratic, the Kullback-Leibler, and the uniform loss.
Weißbach, Rafael, Dette, Holger
core  

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

A Non-Sequential Representation of Sequential Data for Churn Prediction [PDF]

open access: yes, 2009
We investigate the length of event sequence giving best predictions when using a continuous HMM approach to churn prediction from sequential data. Motivated by observations that predictions based on only the few most recent events seem to be the most ...
Eastwood, Mark   +4 more
core   +1 more source

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