Results 71 to 80 of about 104,528 (306)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A Non-Sequential Representation of Sequential Data for Churn Prediction [PDF]
, 2009 We investigate the length of event sequence giving best predictions when using a continuous HMM approach to churn prediction from sequential data. Motivated by observations that predictions based on only the few most recent events seem to be the most ...
Eastwood, Mark +4 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Visible Reverse K-Nearest Neighbor Queries [PDF]
, 2009 — Reverse nearest neighbor (RNN) queries have a broad application base such as decision support, profile-based marketing, resource allocation, data mining, etc. Previous work on RNN search does not take obstacles into consideration.
CHEN, Gencai +12 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Using K-Nearest Neighbor in Optical Character Recognition
ComTech, 2016 The growth in computer vision technology has aided society with various kinds of tasks. One of these tasks is the ability of recognizing text contained in an image, or usually referred to as Optical Character Recognition (OCR).
Veronica Ong, Derwin Suhartono
doaj +1 more source
Secure k-ish Nearest Neighbors Classifier
Proceedings on Privacy Enhancing Technologies, 2020 Abstract The k-nearest neighbors (kNN) classifier predicts a class of a query, q, by taking the majority class of its k neighbors in an existing (already classified) database, S. In secure kNN, q and S are owned by two different parties and q is classified without sharing data.
Shaul, Hayim, Feldman, Dan, Rus, Daniela
openaire +4 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Alternative methods for forecasting GDP [PDF]
An empirical forecast accuracy comparison of the non-parametric method, known as multivariate Nearest Neighbor method, with parametric VAR modelling is conducted on the euro area GDP. Using both methods for nowcasting and forecasting the GDP, through the
Patrick Rakotomarolahy, Dominique Guegan
core +3 more sources