Results 111 to 120 of about 592,656 (330)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Information Retrieval Document Classified with K-Nearest Neighbor

Record and Library Journal, 2018
Along with the rapid advancement of technology development led to the amount of information available is also increasingly abundant. The aim of this study was to determine how the implementation of information retrieval system in the classification of ...
Alifian Sukma, Badruz Zaman, Endah Purwanti   +2 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Emotion recognition from multichannel EEG signals using K-nearest neighbor classification

Technology and Health Care, 2018
BACKGROUND: Many studies have been done on the emotion recognition based on multi-channel electroencephalogram (EEG) signals. OBJECTIVE: This paper explores the influence of the emotion recognition accuracy of EEG signals in different frequency bands and
Mi Li, Hongpei Xu, Xingwang Liu, Shengfu Lu   +3 more
semanticscholar   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Application of Data Mining for Tuberculosis Disease Classification Using K-Nearest Neighbor

Jurnal Sisfokom
This study aims to find out how much the application of the K-NN method and the accuracy value obtained by the K-NN method in clarifying data of Tuberculosis patients. This research focuses on improving public health and developing science to help people
Delima Sitanggang, lamria Simangunsong, Geertruida Frederika Sundah, Rani Hutahaean, Indren Indren   +4 more
doaj   +1 more source

Navigating K-Nearest Neighbor Graphs to Solve Nearest Neighbor Searches [PDF]

, 2010
Nearest neighbor queries can be satisfied, in principle, with a greedy algorithm under a proximity graph. Each object in the database is represented by a node, and proximal nodes in this graph will share an edge. To find the nearest neighbor the idea is quite simple, we start in a random node and get iteratively closer to the nearest neighbor following
Edgar Chávez, Eric Sadit Tellez
openaire   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

K-Nearest Neighbor and Weight K-Nearest Neighbor Classification of Cork Fish Using Gray-Level-Co-Occurrence Matrix Algorithm Approach

JOIV: International Journal on Informatics Visualization
Ornamental cork fish is a type of fish that is in great demand among the public as an ornamental fish. Ornamental cork fish have various types and colors; each variation has its own name and is a selling point among ornamental cork fish lovers.
Euis Nur Fitriani Dewi, Andi Nur Rachman, Rahmi Nur Shofa, Genta Nazwar Tarempa   +3 more
doaj   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source