Results 11 to 20 of about 1,253 (148)

One-Pot Synthesis and Antimicrobial Activity of Novel α-Aminophosphonates Using TMG

E-Journal of Chemistry, 2011
α-Aminophosphonates (4a-j) were synthesized in one-pot simultaneous reaction of 4-bromo-3-methyl benzenamine (1), dimethylphosphite (3) and different aromatic aldehydes (2a-j) by Kabachnik-Fields reaction in the presence of tetramethylguanidine (TMG) (10
B. Siva Kumar, Y. Haranadha Reddy, C. Radha Rani, G. Chnadra Sekhar Reddy   +3 more
doaj   +2 more sources

Preparation of New α-Aminophosphonate Derivatives by Kabachnik-Fields Reaction Using a Recyclable Catalyst

Journal of Chemistry, 2013
A convenient and efficient synthetic method for the preparation of some new α-aminophosphonate derivatives via a one-pot three-component system has been achieved using Amberlite IRC-748 as a recyclable catalyst. This method not only provides an excellent
Nellisara D. Shashikumar
doaj   +2 more sources

Practical and Efficient Synthesis of (E)-α,β-Unsaturated Amides Incorporating α-Aminophosphonates via the Horner–Wadsworth–Emmons Reaction [PDF]

Molecules
An efficient and practical procedure for the synthesis of (E)-α,β-unsaturated amides incorporating α-aminophosphonates, derived from readily accessible phosphonoacetamides, via the Horner–Wadsworth–Emmons (HWE) reaction was developed.
Sindy Anahi Perez-Aniceto, Erica Cano-Tapia, Mario Ordoñez, José Luis Viveros-Ceballos, Ivan Romero-Estudillo   +4 more
doaj   +2 more sources

Ultrafast synthesis of α-aminophosphonates using ternary deep eutectic solvent in water [PDF]

Scientific Reports
A remarkably rapid synthesis of α-aminophosphonate medicinally privileged scaffold is developed using a ternary deep eutectic solvent (TDES) of urea/SnCl2/HCl catalyst.
Najmedin Azizi, Navid Habibnejad, Nasim Nourazar, Mehran Shahiri Haghayegh   +3 more
doaj   +2 more sources

Microwave-Assisted Synthesis of Aminophosphonic Derivatives and Their Antifungal Evaluation against Lomentospora prolificans [PDF]

Molecules, 2023
Lomentospora prolificans is a pathogenic and multidrug-resistant fungus that can infect both immunocompetent and immunocompromised patients, with mortality rates up to 87%.
Zuleyma Martínez-Campos, Mariana Elizondo-Zertuche, Emanuel Hernández-Núñez, Eugenio Hernández-Fernández, Efrén Robledo-Leal, Susana T. López-Cortina   +5 more
doaj   +2 more sources

A new class of anticancer activity with computational studies for a novel bioactive aminophosphonates based on pyrazole moiety [PDF]

Scientific Reports, 2023
The present study involves synthesis a new series of α-aminophosphonates 2a-f and 4a-d derivatives in good yield with a simple workup via Kabachnik-Fields reaction in the presence of lithium perchlorate as Lewis acid catalyst.
Mohamed H. Baren, Seham A. Ibrahim, Munirah M. Al-Rooqi, Saleh A. Ahmed, Mohammed M. El-Gamil, Hend A. Hekal   +5 more
doaj   +2 more sources

Chemical Modification of Acrylonitrile-Divinylbenzene Polymer Supports with Aminophosphonate Groups and Their Antibacterial Activity Testing [PDF]

Molecules
Bacterial contamination is a major public health concern on a global scale. Treatment resistance in bacterial infections is becoming a significant problem that requires solutions.
Ileana Nichita, Lavinia Lupa, Aurelia Visa, Ecaterina-Stela Dragan, Maria Valentina Dinu, Adriana Popa   +5 more
doaj   +2 more sources

Stable, bioactive hydrogel coating on silicone surfaces for non-invasive decontamination via photochemical treatment [PDF]

Bioactive Materials
Polydimethylsiloxane (PDMS) is widely used in biomedical applications due to its biocompatibility, chemical stability, flexibility, and resistance to degradation in physiological environments.
Romina Berger, Alina Rahtz, Alexander Schweigerdt, Daniel D. Stöbener, Andrea Cosimi, Wibke Dempwolf, Henning Menzel, Sonja Johannsmeier, Marie Weinhart   +8 more
doaj   +2 more sources

Facile Conversion of α-Amino Acids into α-Amino Phosphonates by Decarboxylative Phosphorylation using Visible-Light Photocatalysis. [PDF]

Angew Chem Int Ed Engl, 2022
The facile conversion of α‐amino acids to the respective α‐amino phosphonates via their redox active esters using organophotoredox catalysis is reported. A novel photocatalytic phosphorylation combines radical–polar crossover with Arbuzov‐type reactivity, providing an operationally simple, high yielding and general synthetic approach for the generation
Reich D, Noble A, Aggarwal VK.
europepmc   +3 more sources

Ru-Catalyzed Asymmetric Transfer Hydrogenation of α-iminophosphonates: A Novel Synthetic Approach for Valuable Chiral α-Aminophosphonates. [PDF]

Chemistry
This study reports the first Ru‐catalyzed ATH of α‐iminophosphonates, enabling the efficient synthesis of chiral α‐aminophosphonates. Both acyclic and cyclic substrates are converted in high yields (up to 97%) with excellent enantioselectivities (up to >99:1), offering a practical alternative to conventional AH for accessing phosphorus‐containing ...
Plouard P, Borrel L, Butin PO, Muller P, Cherpitel R, Loiseau S, Clarion L, Virieux D, Ayad T.   +8 more
europepmc   +2 more sources