Results 41 to 50 of about 3,243 (180)

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy

Andrology, Volume 14, Issue 1, Page 273-283, January 2026.
Abstract The exploration of gender differences in non‐andrological fields was the core focus of a series of discussions, which took place at the Endocrinology Unit in Modena, Italy in the form of the aporetic dialogue of ancient Greece. This second episode reports the transcript of the actual debate on testosterone's role in defining empathic behavior ...
Giulia Brigante, Clara Lazzaretti, Ali Ahmad, Massimiliano Colzani, Filippo Vignali, Michele Zoli, Manuela Simoni   +6 more
wiley   +1 more source

Clinical and inheritance profiles of Kallmann syndrome in Jordan

Reproductive Health, 2004
Background Proper management of patients with Kallmann syndrome (KS) allows them to attain a normal reproductive health. The purpose of this study is to demonstrate the presentation modalities, phenotypes and the modes of inheritance among 32 patients ...
Shegem Nadima S, Jarrah Nadim S, Hamamy Hanan A, AbuJbara Mousa A, Ajlouni Kamel M   +4 more
doaj   +1 more source

WD40-Repeat Proteins in Ciliopathies and Congenital Disorders of Endocrine System [PDF]

Endocrinology and Metabolism, 2020
WD40-repeat (WDR)-containing proteins constitute an evolutionarily conserved large protein family with a broad range of biological functions. In human proteome, WDR makes up one of the most abundant protein-protein interaction domains. Members of the WDR
Yeonjoo Kim, Soo-Hyun Kim
doaj   +1 more source

High Expression of IGSF10 Confers an Inhibitory Effect on the Progression of Lung Adenocarcinoma

Journal of Cellular and Molecular Medicine, Volume 29, Issue 24, December 2025.
ABSTRACT Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer‐related deaths worldwide. Unlike conventional treatments, the targeted therapies or emerging immunotherapies have shown significant advantages in the management of advanced lung cancer.
Lianyu Cheng, Beibei Ma, Yun Zhao, Chunyan Qin, Lihe Jiang, Bo Ling   +5 more
wiley   +1 more source

Prenatal alcohol exposure perturbs the development of radial glial cells in the fetal olfactory bulb

Alcohol, Clinical and Experimental Research, Volume 49, Issue 11, Page 2494-2501, November 2025.
Prenatal alcohol exposure affects the development of radial glial cells (RGCs) in the embryonic mouse olfactory bulb. Ethanol administered at embryonic day 11, a time point when RGCs generate the largest number of mitral cells, caused G2/M arrest in RGCs, delaying their progression to mitosis and subsequent neuronal differentiation.
Yuka Imamura Kawasawa, Kazue Hashimoto‐Torii, Masaaki Torii, Fumiaki Imamura   +3 more
wiley   +1 more source

New findings in oligogenic inheritance of congenital hypogonadotropic hypogonadism

Archives of Medical Science, 2020
Introduction Congenital hypogonadotropic hypogonadism results from a dysfunction of the hypothalamic-pituitary-gonadal axis, which is essential for the development and function of the reproductive system. It may be associated with anosmia, referred to as
Agnieszka Gach, Iwona Pinkier, Urszula Wysocka, Kinga Sałacińska, Dominik Salachna, Maria Szarras-Czapnik, Aleksandra Pietrzyk, Agata Sakowicz, Anna Nykel, Lena Rutkowska, Magda Rybak-Krzyszkowska, Magda Socha, Aleksander Jamsheer, Lucjusz Jakubowski   +13 more
doaj   +1 more source

Phenotypic spectrum of patients with mutations in CHD7: clinical implications of endocrinological findings

Endocrine Connections, 2022
Objective: Heterozygous CHD7 mutations cause a broad spectrum of clinical phenotypes ranging from typical CHARGE syndrome to self-limited delayed puberty.
Ja Hye Kim, Yunha Choi, Soojin Hwang, Gu-Hwan Kim, Han-Wook Yoo, Jin-Ho Choi   +5 more
doaj   +1 more source

Clinical Predictors of Response to Testosterone Replacement Therapy in Boys With Micropenis: A Retrospective Study Focusing on Penile Morphology and Hormonal Factors

International Journal of Urology, Volume 32, Issue 11, Page 1670-1676, November 2025.
ABSTRACT Objectives We aimed to identify clinical predictors of response to testosterone replacement therapy in boys with micropenis, focusing on initial penile measurements, hormone levels, and treatment timing relative to the mini‐puberty period.
Junki Harada, Kensuke Mitsunari, Shota Kakita, Hajime Fukushima, Haruka Kawamura, Hiroki Kurata, Tsuyoshi Matsuda, Midori Motokawa, Itsuho Ito, Kyohei Araki, Yuichiro Nakamura, Tomohiro Matsuo, Sumito Dateki, Toshiharu Kihara, Kojiro Ohba, Yasushi Mochizuki, Ryoichi Imamura   +16 more
wiley   +1 more source

A novel nonsense mutation of the KAL1 gene (p.Trp204*) in Kallmann syndrome

The Application of Clinical Genetics, 2014
Antonette Souto El Husny,1 Milene Raiol-Moraes,1 Milena Coelho Fernandes-Caldato,2,3 Ândrea Ribeiro-dos-Santos1 1Laboratory of Human and Medical Genetics, Federal University of Pará, 2João de Barros Barreto University Hospital ...
El Husny AS, Raiol-Moraes M, Fernandes-Caldato MC, Ribeiro-dos-Santos    +3 more
doaj  

Kallmann Syndrome - causes, symptoms, treatment - review of literature

Quality in Sport
Background: Kallmann syndrome is a rare congenital disorder characterized by hypogonadotropic hypogonadism and anosmia or hyposmia. KS results from abnormalities in the migration of GnRH neurons from the nasal placode to the hypothalamus.
Natalia Żak
doaj   +1 more source