Results 71 to 80 of about 2,952 (186)

A career in numbers: A citation network analysis of the work of RP Millar and his contribution to GnRH research

open access: yesJournal of Neuroendocrinology, Volume 36, Issue 10, October 2024.
Here, we use citation network analysis in a novel manner to identify the particular topics to which RP Millar's papers have made a particular contribution. This analysis shows that it makes no sense to conceive of the citation impact of an author in isolation; it depends on the existence of a receptive community that is alert to the potential utility ...
Rhodri I. Leng, Gareth Leng
wiley   +1 more source

Kallmann's syndrome: clues to clinical diagnosis [PDF]

open access: yesInternational Journal of Impotence Research, 2000
Hypogonadotropic patients may visit pediatricians, general practitioners, endocrinologists or urologists, presenting with microphallus, cryptochidism or pubertas tarda and delayed bone maturation. Congenital hypogonadotropic hypogonadism is characterized, apart from small testes, by the constellation of low serum levels of testosterone, LH and FSH ...
Christoph Schmid, Hubert John
openaire   +5 more sources

Response to “Gonadotropin Treatment of Cryptorchidism in Congenital Hypogonadotropic Hypogonadism—Age Is No Limit?”

open access: yes
Clinical Endocrinology, Volume 102, Issue 6, Page 706-707, June 2025.
Yoon Hi Cho   +3 more
wiley   +1 more source

Current landscape of fertility induction in males with congenital hypogonadotropic hypogonadism

open access: yesAnnals of the New York Academy of Sciences, Volume 1540, Issue 1, Page 133-146, October 2024.
Congenital hypogonadotropic hypogonadism (CHH) is a treatable form of male infertility amenable to hormonal treatment. Approximately 75%–80% of males with CHH can develop sperm in the ejaculate, and low sperm counts do not preclude fertility. Important early life determinants (i.e., minipuberty) affect future fertility potential. Identifying predictors
Andrew A. Dwyer   +2 more
wiley   +1 more source

Kisspeptin in functional hypothalamic amenorrhea: Pathophysiology and therapeutic potential

open access: yesAnnals of the New York Academy of Sciences, Volume 1540, Issue 1, Page 21-46, October 2024.
This review evaluates the physiological regulation of pulsatile gonadotropin‐releasing hormone (GnRH) secretion and the downstream reproductive axis by hypothalamic kisspeptin neurons and how their activity is modulated by peripheral signals of energy status.
Aaran H. Patel   +6 more
wiley   +1 more source

Hypogonadotropic Hypogonadism Associated with Hereditary Hemorrhagic Telengiectasia

open access: yesCase Reports in Endocrinology, 2013
A 65-year-old man was referred to our clinic for the rehabilitation of right hemiparesis caused by ischaemic stroke. Hypertension, postphlebitic syndrome of lower limbs, frequent nose bleeding, and anemia were present in his history; in his adolescence ...
Scarano Valentina   +6 more
doaj   +1 more source

Luxenburger's 1939 Essay on “Schizophrenia and its Hereditary Circle”

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 195, Issue 6, September 2024.
Abstract In 1939, Hans Luxenburger published a detailed overview of the current status of schizophrenia genetics research, reaching six major conclusions. First, schizophrenia is clearly a hereditary disease. Second, however, schizophrenia is not the hereditary trait itself but rather the consequences of a slowly developing biological progress, the ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Zebrafish adult-derived hypothalamic neurospheres generate gonadotropin-releasing hormone (GnRH) neurons

open access: yesBiology Open, 2015
Gonadotropin-releasing hormone (GnRH) is a hypothalamic decapeptide essential for fertility in vertebrates. Human male patients lacking GnRH and treated with hormone therapy can remain fertile after cessation of treatment suggesting that new GnRH neurons
Christian Cortés-Campos   +3 more
doaj   +1 more source

Restoring function to inactivating G protein‐coupled receptor variants in the hypothalamic–pituitary–gonadal axis1

open access: yesJournal of Neuroendocrinology, Volume 36, Issue 9, September 2024.
Pharmacological chaperones (PC's) are an emerging class of cell permeant small molecules that can stabilise the folding of misfolded variant proteins, thus restoring function. G protein‐coupled receptors (GPCRs) are a family of plasma membrane associated receptors that have been shown to be amenable to PC rescue.
Tarryn Radomsky   +3 more
wiley   +1 more source

Reproduction, Smell and Neurodevelopmental disorders: Genetic defects in different hypogonadotropic hypogonadal syndromes.

open access: yesFrontiers in Endocrinology, 2014
The neuroendocrine control of reproduction in mammals is governed by a neural hypothalamic network of nearly 1500 gonadotropin-releasing hormone (GnRH) secreting neurons that modulate the activity of the reproductive axis across life.
Hernan G VALDES-SOCIN   +5 more
doaj   +1 more source

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