Results 71 to 80 of about 2,952 (186)
Here, we use citation network analysis in a novel manner to identify the particular topics to which RP Millar's papers have made a particular contribution. This analysis shows that it makes no sense to conceive of the citation impact of an author in isolation; it depends on the existence of a receptive community that is alert to the potential utility ...
Rhodri I. Leng, Gareth Leng
wiley +1 more source
Kallmann's syndrome: clues to clinical diagnosis [PDF]
Hypogonadotropic patients may visit pediatricians, general practitioners, endocrinologists or urologists, presenting with microphallus, cryptochidism or pubertas tarda and delayed bone maturation. Congenital hypogonadotropic hypogonadism is characterized, apart from small testes, by the constellation of low serum levels of testosterone, LH and FSH ...
Christoph Schmid, Hubert John
openaire +5 more sources
Clinical Endocrinology, Volume 102, Issue 6, Page 706-707, June 2025.
Yoon Hi Cho+3 more
wiley +1 more source
Current landscape of fertility induction in males with congenital hypogonadotropic hypogonadism
Congenital hypogonadotropic hypogonadism (CHH) is a treatable form of male infertility amenable to hormonal treatment. Approximately 75%–80% of males with CHH can develop sperm in the ejaculate, and low sperm counts do not preclude fertility. Important early life determinants (i.e., minipuberty) affect future fertility potential. Identifying predictors
Andrew A. Dwyer+2 more
wiley +1 more source
Kisspeptin in functional hypothalamic amenorrhea: Pathophysiology and therapeutic potential
This review evaluates the physiological regulation of pulsatile gonadotropin‐releasing hormone (GnRH) secretion and the downstream reproductive axis by hypothalamic kisspeptin neurons and how their activity is modulated by peripheral signals of energy status.
Aaran H. Patel+6 more
wiley +1 more source
Hypogonadotropic Hypogonadism Associated with Hereditary Hemorrhagic Telengiectasia
A 65-year-old man was referred to our clinic for the rehabilitation of right hemiparesis caused by ischaemic stroke. Hypertension, postphlebitic syndrome of lower limbs, frequent nose bleeding, and anemia were present in his history; in his adolescence ...
Scarano Valentina+6 more
doaj +1 more source
Luxenburger's 1939 Essay on “Schizophrenia and its Hereditary Circle”
Abstract In 1939, Hans Luxenburger published a detailed overview of the current status of schizophrenia genetics research, reaching six major conclusions. First, schizophrenia is clearly a hereditary disease. Second, however, schizophrenia is not the hereditary trait itself but rather the consequences of a slowly developing biological progress, the ...
Kenneth S. Kendler, Astrid Klee
wiley +1 more source
Gonadotropin-releasing hormone (GnRH) is a hypothalamic decapeptide essential for fertility in vertebrates. Human male patients lacking GnRH and treated with hormone therapy can remain fertile after cessation of treatment suggesting that new GnRH neurons
Christian Cortés-Campos+3 more
doaj +1 more source
Pharmacological chaperones (PC's) are an emerging class of cell permeant small molecules that can stabilise the folding of misfolded variant proteins, thus restoring function. G protein‐coupled receptors (GPCRs) are a family of plasma membrane associated receptors that have been shown to be amenable to PC rescue.
Tarryn Radomsky+3 more
wiley +1 more source
The neuroendocrine control of reproduction in mammals is governed by a neural hypothalamic network of nearly 1500 gonadotropin-releasing hormone (GnRH) secreting neurons that modulate the activity of the reproductive axis across life.
Hernan G VALDES-SOCIN+5 more
doaj +1 more source