Clinical evaluation of the CrossNN DNA methylation classifier for central nervous system tumors. [PDF]
CrossNN demonstrated non‐inferiority to the Heidelberg CNS Tumor Methylation Classifier. A dual‐classifier approach increased the number of clinically informative classifications with correct tumor type assignment while maintaining a low rate of incorrect predictions.
Dahnoun J +8 more
europepmc +2 more sources
Hypoxia Induces a Mitotic Survival Advantage After Radiotherapy in Head and Neck Cancer Cells. [PDF]
Hypoxic tumor environments significantly limit radiotherapy effectiveness against cancer, particularly in head and neck squamous cell carcinoma (HNSCC). Here, the authors tracked hypoxic and post‐hypoxic cells using a hypoxia‐fate mapping system in human papillomavirus (HPV)‐positive and HPV‐negative HNSCC models.
Wegge M, Dok R, Dubois LJ, Nuyts S.
europepmc +2 more sources
Twenty-year results of the randomized European Organization for Research and Treatment of Cancer trial 22922/10925 evaluating internal mammary chain and medial supraclavicular lymph node irradiation in stage I-III breast cancer. [PDF]
Abstract European Organization for Research and Treatment of Cancer trial EORTC 22922/10925 evaluated internal mammary and medial supraclavicular (IM‐MS) lymph node irradiation (IM‐MS‐RT) in patients with stage I–III breast cancer. Eligible patients had involved axillary nodes and/or centrally/medially located tumors regardless of nodal involvement ...
Kaidar-Person O +24 more
europepmc +2 more sources
Studi Tinjauan Pustaka: Risiko Kejadian Kanker Paru pada Penderita Tuberkulosis Paru. [PDF]
Indonesia merupakan satu dari lima negara di dunia dengan insiden kasus TB yang tinggi, sementara itu kanker paru di Indonesia merupakan kasus keganasan utama yang paling sering terjadi.
Syarif, Syahrizal, Ramadhaniah, Fariha
core +1 more source
In vitro and in silico modelling of ROS1-positive non-small cell lung cancer reveals fusion-dependent tyrosine kinase inhibitor responses. [PDF]
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Ul Haq F +8 more
europepmc +2 more sources
A Syndecan-Based Genetic Approach to Coat the Surface of Small Extracellular Vesicles With Nanobodies. [PDF]
ABSTRACT Small extracellular vesicles (sEVs) are promising vehicles for targeted therapeutic delivery, but strategies for their surface functionalization remain limited. Here, we present a reliable and simple genetic approach that enables customized modification of sEV surfaces and supports enhanced sEV uptake by recipient cells. This strategy is based
Hyka L +7 more
europepmc +2 more sources
Kebijakan dan Pokok-pokok Kegiatan Pengendalian Penyakit Kanker di Indonesia
Pengendalian penyakit kanker di Indonesia telah banyak dilakukan oleh berbagai pihak baik pemerintah maupun non pemerintah, namun belum berjalan secara terpadu, komprehensif, dan berkesinambungan.
Achmad Hardiman +2 more
doaj +1 more source
Efektivitas Terapi Akupunktur untuk Tata Laksana Adjuvan Nyeri Kanker
Latar belakang. Efektivitas terapi akupunktur untuk tatalaksana adjuvan nyeri kanker pada anak masih kontroversial. Tujuan. Melakukan telaah kritis untuk menilai efektivitas terapi akupunktur untuk tatalaksana adjuvan nyeri kanker pada anak.
Murti Andriastuti +2 more
doaj +1 more source
Kewaspadaan Terhadap Kanker Pada Perempuan Keturunan Pasien Kanker Payudara
Faktor genetik memegang peran pen ting penyebab terjadinya kanker payudara. Terutama pada anak dari ibu yang terkena kanker payudara memiliki kesempatan 2 kali lebih besar terkena kanker payudara.
Boby Febri Krisdianto +3 more
doaj +1 more source
Kebijakan Pengendalian Penyakit Kanker (Serviks) di Indonesia
Terjadi perubahan pola penyakit dari penyakit infeksi ke penyakit noninfeksi di dunia, termasuk Indonesia. Salah satu penyakit non-infeksi adalah kanker. Badan kesehatan dunia (WHO) sudah mengeluarkan resolusi perang terhadap kanker.
Bambang Dwipoyono
doaj +1 more source

