Results 191 to 200 of about 997,609 (339)
DaxibotulinumtoxinA for Injection in Adults with Cervical Dystonia: Clinical Insights from a Real‐World Early Experience Program
Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background
DaxibotulinumtoxinA for injection (DAXI), a novel botulinum toxin (BoNT) formulated with a custom‐engineered peptide, was recently approved for treating cervical dystonia (CD). DAXI demonstrated a long duration of symptom relief in Phase 3 trials. Objective
To report findings from PrevU, an early experience, real‐world observational Laxman Bahroo, Aaron Ellenbogen, Robert A. Hauser, Han S. Lee, Peter McAllister, Atul T. Patel, Rashid Kazerooni, Todd M. Gross, Julia Sparrow, Conor J. Gallagher, David A. Hollander +10 morewiley +1 more sourceConsiderations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease
Movement Disorders Clinical Practice, EarlyView.Abstract Background
As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been K. Ray Chaudhuri, Bruno Bergmans, Eric Freire‐Alvarez, Lucie Hopes, Drew S. Kern, Robert S. Kirsner, Giulia Lazzeri, Pedro Mendes‐Bastos, Noriko Nishikawa, Per Odin, Karolina Poplawska‐Domaszewicz, Rajesh Pahwa, Yuval Ramot, Klaus Seppi, Tobias Warnecke, Robert Wiggins, Megha B. Shah, Pavnit Kukreja, Bjoern Fritz, Koray Onuk, Stuart H. Isaacson +20 morewiley +1 more sourceUpdate on Medical Treatments for Essential Tremor: An International Parkinson and Movement Disorder Society Evidence‐Based Medicine Review
Movement Disorders, EarlyView.Abstract Background
The first International Parkinson and Movement Disorder Society Evidence‐Based Medicine (MDS‐EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology was adopted by MDS, and new evidence exists.Deepa Dash, Verónica Bruno, Petra Schwingenschuh, Kelly E. Lyons, Eng‐King Tan, Claudia M. Testa, Santiago Perez Lloret, Bettina Balint, João Costa, Rob M.A. de Bie, Monty A. Silverdale, Ai Huey Tan, Tiago A. Mestre +12 morewiley +1 more sourceTesting the effects of a text message intervention on depression and distress among Latino dementia caregivers: A randomized controlled trial protocol. [PDF]
Contemp Clin TrialsPerales-Puchalt J, Ramírez-Mantilla M, Moore HP, Velez-Uribe I, Sepulveda-Rivera V, Ruiz R, Fracachán-Cabrera M, Herrera Y, Baker C, Miras-Neira A, Bothwell B, Anderson H, Lewandowski T, Diaz FJ, Greiner KA, Williams K, Vidoni ED, Ellerbeck E, Burns JM. +18 moreeuropepmc +1 more sourceDynamics of Nerve Conduction Studies in Patients With Guillain–Barré Syndrome
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims
The value of electrodiagnostic subtyping of Guillain–Barré syndrome (GBS) is still debated. This study aimed to determine the diagnostic yield, timing, and changes of the electrodiagnostic subtyping in patients with GBS in serial nerve conduction studies (NCS).Samuel Arends, Laura de Koning, Judith Drenthen, Mahova Zhu, Peter Y. K. van den Bergh, Robert M. Hadden, Nortina Shahrizaila, Ricardo C. Reisin, Satoshi Kuwabara, Senda Ajroud‐Driss, Giovanni Antonini, Claudia Balducci, Fabio A. Barroso, Thomas H. Brannagan, Jan Buermann, Carlos Casasnovas, Guido Cavaletti, Chi‐Chao Chao, Ulrich Dillmann, Mazen M. Dimachkie, Giuliana Galassi, Gerardo Gutiérrez‐Gutiérrez, Thomas Harbo, Sung‐Tsang Hsieh, Badrul Islam, Hans Katzberg, Lynette Kiers, Giorgia Mataluni, Julio Pardo, Yann Peréon, Yusuf A. Rajabally, Mark Stettner, Camiel Verhamme, Michal Vytopil, Waheed Waqar, David R. Cornblath, Bart C. Jacobs, IGOS Consortium, James M. Addington, Senda Ajroud‐Driss, Hiroshi Amino, Giovanni Antonini, Sharam Attarian, Umesh A. Badrising, Claudia Balducci, Fabio A. Barroso, Kathleen Bateman, Isabelita Bella, Luana Benedetti, Tulio Bertorini, Ratna Bhavaraju‐Sanka, Davide Binda, Thomas Brannagan, Chiara Briani, Jan Buermann, Mark Busby, Steven Butterworth, Carlos Casasnovas, Guido Cavaletti, Govind Chavada, Chi‐Chao Chao, Shan Chen, Kristl Claeys, Eugenia Conti, Jeremy S. Cosgrove, Marinos Dalakas, Philip van Damme, Efthimios Dardiotis, Amy Davidson, Ulrich Dillmann, Mazen Dimachkie, Alex Doets, Pieter van Doorn, Andoni Echaniz‐Laguna, Filip Eftimov, Karin G. Faber, Raffaella Fazio, Thomas E. Feasby, Janev Fehmi, Chris Fokke, Toshiki Fujioka, Ernesto Fulgenzi, Giuliana Galassi, Marcel P.J. Garssen, Cees J. Gijsbers, James M. Gilchrist, Job Gilhuis, Jonathan M. Goldstein, Kenneth C. Gorson, Namita Goyal, Volkan Granit, Gerardo Gutiérrez‐Gutiérrez, Ludwig Gutmann, Thomas Harbo, Hans‐Peter Hartung, James K.L. Holt, Sung‐Tsang Hsieh, Min Htut, Richard A.C. Hughes, Badrul Islam, Zhahirul Islam, Ivonne Jericó‐Pascual, Kenichi Kaida, Summer Karafiath, Hans Katzberg, Mohammad Ali Khoshnoodi, Lynette Kiers, Ruud P. Kleiweg, Norito Kokubun, Noah A. Kolb, Rinske van Koningsveld, Anneke J. van der Kooi, Hans Kramers, Krista Kuitwaard, Justin Y. Kwan, Shafeeq S. Ladha, Lisbeth Landschoff Lassen, Victoria H. Lawson, Helmar Lehmann, Luciana Leon Cejas, Linda Luijten, Michael P.T. Lunn, Fiore Manganelli, Hadi Manji, Girolama A. Marfia, Celedonio Márquez Infante, Lorena Martín‐Aguilar, Eugenia Martinez‐Hernandez, Giorgia Mataluni, Marcelo Mattiazzi, Christopher McDermott, Gregg Meekins, Quazi Deen Mohammad, Soledad Monges, Germán Moris de la Tassa, Caterina Nascimbene, Eduardo Nobile‐Orazio, Richard J. Nowak, Michael Osei‐Bonsu, Julio Pardo, Farah Pelouto, Yann Péreon, Michael T. Pulley, Luis Querol Gutiérrez, Yusuf Rajabally, Stephen W. Reddel, Taco van der Ree, Simon Rinaldi, Paolo Ripellino, Rhys C. Roberts, Iñigo Rojas‐Marcos, Stacy A. Rudnicki, George M. Sachs, Johnny P.A. Samijn, Lucio Santoro, Angelo Schenone, Maria José Sedano Tous, Yukari Sekiguchi, Kazim A. Sheikh, Nicholas Joseph Silvestri, Soeren H. Sundrup, Claudia Sommer, Beth Stein, Mark Stettner, Amro Maher Stino, Robin C.M. Thomma, Paul Twydell, Giovanni Uncini, Jay D. Varrato, Camiel Verhamme, Frederique H. Vermeij, Jan Verschuuren, Leo H. Visser, Michal Vytopil, Christa Walgaard, Min Wang, Yuzhong Wang, Waheed Waqar, Hugh J. Willison, Paul W. Wirtz, Marieke van Woerkom, Sascha A. Zivkovic +181 morewiley +1 more sourceHuman CNTNAP1 Variants Associated With Severe Neurological Deficits: Additional Cases and Literature Review
Muscle &Nerve, EarlyView.ABSTRACT
CNTNAP1 encodes the Contactin‐Associated Protein 1 (CNTNAP1), also known as Caspr1, which is a transmembrane protein critical for nervous system function. CNTNAP1 is localized to the paranodal regions of all myelinated axons, flanking either side of the node of Ranvier.Lacey B. Sell, Derek Garcia, Alexandra Hollá, Ilana Chilton, Seth DeVries, Ana María Gómez‐Moreno, Manuel Lubián‐Gutiérrez, Qian Shi, Manzoor A. Bhat +8 morewiley +1 more sourceCurrent state of neonatal intestinal rehabilitation care in North America: A descriptive survey‐based study
Nutrition in Clinical Practice, EarlyView.Abstract Background
Multidisciplinary care under intestinal rehabilitation programs (IRPs) improves survival in pediatric intestinal failure (IF). Professional societies recommend the management of pediatric patients with IF by an IRP. Whether these recommendations are followed in cases of neonatal IF is currently unclear.Katie A. Huff, Ethan A. Mezoff, Abeer Azzuqa, Darren Bodkin, Hannah Hightower, Mark R. Corkins, Jeffery A. Rudolph, Katie M. Strobel, Jae H. Kim, Muralidhar H. Premkumar, Sujir Pritha Nayak, the Children's Hospitals Neonatal Consortium Intestinal Failure Focus Group +11 morewiley +1 more sourceWeekly Subcutaneous VK2735, a GIP/GLP‐1 Receptor Dual Agonist, for Weight Management: Phase 2, Randomized, 13‐Week VENTURE Study
Obesity, EarlyView.Four doses of VK2735 and a placebo group were included in the VENTURE study. Adults who were overweight or had obesity had significant weight loss when taking any dose of VK2735 for 13 weeks. More people lost at least 10% of their body weight as the dose increased.Harold E. Bays, Phillip Toth, Naim Alkhouri, John Pullman, Bradley Freilich, Joel Neutel, Summer Ji, Scott Stubbe, Parke Hedges, Brian Lian +9 morewiley +1 more source
