Results 61 to 70 of about 45,041 (213)
Czy uniwersytet potrzebuje strategii [PDF]
, 2016 The authors present the arguments in favour of strategic planning at the universities. They show how necessary it is to build new visions of the universities and to define their mission, to select their domain of action and develop competitive supremacy.
Dominiak, Piotr, Leja, Krzysztof
core +1 more source
The Outline of the Greek Church Anthropology [PDF]
, 2015 The lecture deals with the peculiarity of the anthropology of Eastern Christians, which in broad outline is already present in the writings of many Greek Fathers. It consists especially in considering state of divine grace as divinisation (théôsis) of
Huculak, Benedykt J.
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The Influence of The Religiousness of Engaged Couples on Their Views Regarding Conception Control and Abortion [PDF]
, 2014 The main purpose of marriage ought to be active love, in other words, procreation- oriented fertile love. One notices, however, that the moral and social norms regarding this issue have presently undergone a far-reaching process of individualisation ...
Kamiński, Krzysztof
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The attitude of the Orthodox Church towards people living in extra-marital relationships [PDF]
, 2014 The aim of this paper is to show the attitude of the Orthodox Church towards extra-marital relationships. This approach is based on two pillars of the Church: theology and the Canon Law, where the second one is subjected to the first one.
Ławreszuk, Marek
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source