Results 41 to 50 of about 737,568 (236)
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
BackgroundBladder cancer lacks useful and robust prognostic markers to stratify patients at risk. Our study is to identify a robust prognostic marker for bladder cancer.MethodsThe transcriptome and clinical data of bladder cancer were downloaded from ...
Jiaxing Lin +6 more
doaj +1 more source
Kaplan-Meier V- and U-statistics
In this paper, we study Kaplan-Meier V- and U-statistics respectively defined as $\theta(\widehat{F}_n)=\sum_{i,j}K(X_{[i:n]},X_{[j:n]})W_iW_j$ and $\theta_U(\widehat{F}_n)=\sum_{i\neq j}K(X_{[i:n]},X_{[j:n]})W_iW_j/\sum_{i\neq j}W_iW_j$, where $\widehat{
Fernández, Tamara, Rivera, Nicolás
core +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The 5-year survival rate is a good prognostic indicator for patients with Gastric cancer that is usually estimated based on Kaplan-Meier. In situations where censored observations are too many, this method produces biased estimations. This study aimed to
Ali Zare +5 more
doaj
Survival Analysis Using Auxiliary Variables Via Nonparametric Multiple Imputation [PDF]
We develop an approach, based on multiple imputation, that estimates the marginal survival distribution in survival analysis using auxiliary variable to recover information for censored observations.
Commenges, Daniel +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Meteorological and Agricultural Drought Risk Assessment via Kaplan–Meier Survivability Estimator
Dry periods and drought are inherent natural occurrences. However, due to the increasing pressures of global warming and climate change, these events have become more frequent and severe on a global scale.
Cem Polat Cetinkaya, Mert Can Gunacti
doaj +1 more source
Survival and Factors Affecting it in Lung Cancer Patients Referred to Imam Khomeini Clinic in Hamadan Province [PDF]
Background: Lung cancer is one of the most common cancers and the leading cause of death due to cancer in the world. It has the highest mortality rate compared to breast, prostate, and other cancers.
Fatemeh Gohari-Ensaf +3 more
doaj +1 more source
Feasibility and Efficacy of Definitive Radiotherapy with 66 Gy and Concurrent Carboplatin-Paclitaxel Chemotherapy for Stage III Non-Small Cell Lung Cancer. [PDF]
Purpose/Objectives : This study was conducted to assess the feasibility and efficacy of definitive radiotherapy (RT) with a total dose of 66 Gy and concurrent carboplatin-paclitaxel chemotherapy for patients (pts) with stage Ⅲ non-small celllung cancer ...
Asakawa, Isao +7 more
core

