Results 61 to 70 of about 16,107 (219)

Strong representation of the Kaplan–Meier and hazard estimators for censored data with m-widely acceptable dependence

open access: yesStatistical Theory and Related Fields
This paper investigates the asymptotic properties of the Kaplan–Meier and hazard estimators for censored survival time data. We conduct this analysis under the assumption of m-widely acceptable (m-WA) dependence, a generalized form of weak correlation ...
Ikhlasse Chebbab
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Cumulative hazard ratio estimation for adverse events data from two-stage dynamic treatment regimes

open access: yesFrontiers in Applied Mathematics and Statistics
Accurate analysis of adverse events in two-stage dynamic treatment regimes is complicated by the presence of competing risks, such as death, which can preclude the observation of an adverse event and introduce bias into standard survival estimates.
Sifiso Vilakati
doaj   +1 more source

Survival in the pre-senile dementia frontotemporal lobar degeneration with TDP-43 proteinopathy: effects of genetic, demographic and neuropathological variables

open access: yesFolia Neuropathologica, 2016
Factors associated with survival were studied in 84 neuropathologically documented cases of the pre-senile dementia frontotemporal dementia lobar degeneration (FTLD) with transactive response (TAR) DNA-binding protein of 43 kDa (TDP-43) proteinopathy ...
Richard A. Armstrong
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Characterization of the variable cow's age at last calving as a measurement of longevity by using the Kaplan–Meier estimator and the Cox model

open access: yesAnimal, 2013
In most studies on beef cattle longevity, only the cows reaching a given number of calvings by a specific age are considered in the analyses. With the aim of evaluating all cows with productive life in herds, taking into consideration the different forms
S.L. Caetano   +7 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN JOB SEEKING DURATION AND THE TIME OF UNEMPLOYMENT BENEFIT. SEARCHING THEORY ON LABOUR MARKET

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2014
The aim of the article is to analyze the influence of time of unemployment benefit on the time of registered unemployment. In research were used a duration analysis methods (Kaplan-Meier estimator, Cox regression model).
Iwona Markowicz
doaj  

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