Results 91 to 100 of about 737,420 (294)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
A Robust Gene Expression Prognostic Signature for Overall Survival in High-Grade Serous Ovarian Cancer. [PDF]
, 2019 The objective of this research was to develop a robust gene expression-based prognostic signature and scoring system for predicting overall survival (OS) of patients with high-grade serous ovarian cancer (HGSOC).
Hang, Bo +8 more
core
Brainstem metastases treated with Gamma Knife stereotactic radiosurgery: the Indiana University Health experience [PDF]
, 2018 Brainstem metastases offer a unique challenge in cancer treatment, yet stereotactic radiosurgery (SRS) has proven to be an effective modality in treating these tumors.
Ansari, Shaheryar +9 more
core +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A decision-theoretic method for analyzing crossing survival curves in healthcare
Healthcare AnalyticsThe problem of crossing Kaplan–Meier curves has not been solved in the medical research literature to date. This paper integrates survival curve comparisons into decision theory, providing a theoretical framework and a solution to the problem of crossing
Elie Appelbaum +3 more
doaj +1 more source
Journal of Craniomaxillofacial Research, 2023 Background: Squamous cell carcinoma (SCC) is the most common malignancy of the oral cavity with multiple complications associated with the disease and its treatments and a high mortality rate.
Ata Garajei, Sarah Pishva, Azadeh Emami
doaj
Analisis Kurva Survival Kaplan Meier pada Pasien HIV/AIDS dengan Antiretroviral Therapy (ART) di RSUD Prof. Dr. Soekandar Kabupaten Mojokerto Menggunakan Uji Log Rank [PDF]
, 2016 HIV/AIDS menjadi masalah kesehatan global hingga saat ini. Namun, laporan UNAIDS menyebutkan pada tahun 2012 mengalami penurunan sebesar 33%, salah satunya disebabkan oleh Antirteroviral Therapy (ART).
Kusumawardani, N. A. (Nurcahyati) +2 more
core
Modified Weighted Kaplan-Meier Estimator
Pakistan Journal of Statistics and Operation Research, 2007 En muchos estudios médicos, la mayoría de los sujetos del estudio no llegan al evento de interés durante el período de estudio. En tales situaciones, el estimador de Kaplan Meier puede estimar las probabilidades de supervivencia para la observación censurada.
Mohammad Shafiq +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Survival Analysis and its Associated Factors of Beta Thalassemia Major in Hamadan Province
Iranian Journal of Medical Sciences, 2015 Background: There currently is a lack of knowledge about the long-term survival of patients with beta thalassemia (BT), particularly in regions with low incidence of the disease.
Reza Zamani +2 more
doaj