Results 81 to 90 of about 737,420 (294)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Duration of Regional Unemployment Spells in Slovenia [PDF]

The paper begins with an overview of the unemployment rate in Slovenia and focuses on duration of unemployment and regional characteristics of the unemployment rates.
Alenka Kavkler, Darja Borsic
core  

Comparisons Between the Kaplan-Meier Complement and the Cumulative Incidence for Survival Prediction in the Presence of Competing Events [PDF]

, 2013
Estimating cumulative event probabilities in time-to-event data can be complicated by competing events. Competing events occur when individuals can experience events other than the primary event of interest.
Borrebach, Jeffrey D.
core   +1 more source

Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study. [PDF]

, 2017
Background Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus ...
Baeten, Kurt, Connelly, Mark C, D'Haese, David, Flynt, Amy, Gross, Steve, McCleod, Michael, Morano, Carrie, Peek, Victoria L, Polzer, John, Raddad, Eyas, Repollet, Madeline, Roberson, Stephanie, Salgia, Ravi, Sanders, Renouard, Spigel, David R, Stille, John R, Um, Suzane L, Weaver, R Waide, Wijayawardana, Sameera R, Yan, S Betty   +19 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Survival Analysis of Breast Tumor in Al-Najaf

Journal of Kufa for Mathematics and Computer, 2011
Breast cancer is the most common type of tumor in Iraq. This research is mainly concerned with study analysis of breast tumor data.  A  representative random sample of patient suffering from tumor was collected from Al-Sadder hospital in Al-Najaf city.
Nazera Khalil Dakhil, Yahya Mahdi Al-mayali, Muna Abbas Mseer   +2 more
doaj   +1 more source

Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database [PDF]

, 2017
For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were ...
Bradley, Jeffrey D, Kozower, Benjamin, Lockhart, A. Craig, Meyers, Bryan F, Parikh, Parag J, Perkins, Stephanie M, Puri, Varun, Roach, Michael C, Robinson, Cliff G, Samson, Pamela P, Vlacich, Gregory   +10 more
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Survival and dispersal of a defined cohort of Irish cattle

Irish Veterinary Journal, 2009
An understanding of livestock movement is critical to effective disease prevention, control and prediction. However, livestock movement in Ireland has not yet been quantified. This study has sought to define the survival and dispersal of a defined cohort
Ashe S, More SJ, O'Keeffe J, White P, McGrath G, Aznar I   +5 more
doaj   +1 more source

Using Kaplan – Meier curves for preliminary evaluation the duration of unemployment spells [PDF]

In this study we present the results of basic data analysis of the duration of unemployment spells in Gorj County using Kaplan – Meier curves The database includes individual information about all the subjects registered at the county agency of Gorj ...
Babucea, Ana-Gabriela, Danacica, Daniela-Emanuela   +1 more
core   +1 more source