Results 41 to 50 of about 730,949 (275)

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt   +76 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Inferences for current chronic graft-versus-host-disease free and relapse free survival

open access: yesBMC Medical Research Methodology, 2022
This paper provides the methodologies of a new summary curve that measures the dynamic outcome following allogenic hematopoietic cell transplantation.
Xu Zhang   +2 more
doaj   +1 more source

Survival Analysis Using Auxiliary Variables Via Nonparametric Multiple Imputation [PDF]

open access: yes, 2004
We develop an approach, based on multiple imputation, that estimates the marginal survival distribution in survival analysis using auxiliary variable to recover information for censored observations.
Commenges, Daniel   +3 more
core   +1 more source

Hepatic resection for metastatic colorectal adenocarcinoma: A proposal of a prognostic scoring system [PDF]

open access: yes, 1999
Background: Hepatic resection for metastatic colorectal cancer provides excellent longterm results in a substantial proportion of patients. Although various prognostic risk factors have been identified, there has been no dependable staging or prognostic ...
Bonham, AC   +9 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Inferensi Fungsi Ketahanan Dengan Metode Kaplan-meier [PDF]

open access: yes, 2006
. Let T be a nonnegatif random variable representing the life time of individuals in some population. Life time data of individuals are devided in two kinds, cencored and uncencored data. The probability of an individual surviving till time t is given by
Andriani, N. S. (Nasichah)   +1 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Kaplan-Meier V- and U-statistics

open access: yes, 2020
In this paper, we study Kaplan-Meier V- and U-statistics respectively defined as $\theta(\widehat{F}_n)=\sum_{i,j}K(X_{[i:n]},X_{[j:n]})W_iW_j$ and $\theta_U(\widehat{F}_n)=\sum_{i\neq j}K(X_{[i:n]},X_{[j:n]})W_iW_j/\sum_{i\neq j}W_iW_j$, where $\widehat{
Fernández, Tamara, Rivera, Nicolás
core   +1 more source

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