Results 51 to 60 of about 2,137,881 (310)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Time-to-event analysis

Perspectives in Clinical Research
Survival analysis (or time-to-event analysis) deals with data where the outcome of interest is the length of time until the occurrence of an event. This type of analysis is unique because the event may not occur in all participants (known as censoring ...
Priya Ranganathan, Vishal Deo, C. S. Pramesh   +2 more
doaj   +1 more source

Robust bias estimation for Kaplan–Meier survival estimator with jackknifing [PDF]

Journal of Statistical Theory and Practice, 2015
17 pages, 3 figures, 5 tables. CRiSM working paper, Paper No.
Khan, Md. Hasinur Rahaman, Shaw, J. Ewart H.   +1 more
openaire   +3 more sources

Kaplan-Meier survival estimate for investing and non-investing firms (micro firms).

, 2016
Kaplan-Meier survival estimate for investing and non-investing firms (micro firms).
Dejan Kovac (2936430), Vuk Vukovic (817607), Boris Podobnik (709142), Nikola Kleut (2936427)   +3 more
core   +1 more source

Kaplan-Meier survival estimate of asphyxiated newborns admitted to the NICU of DCSH, Amhara region, Northeast Ethiopia (N = 378).

, 2022
Kaplan-Meier survival estimate of asphyxiated newborns admitted to the NICU of DCSH, Amhara region, Northeast Ethiopia (N = 378).
Yibeltal Asmamaw Yitayew (11826417), Zemen Mengesha Yalew (11826414)   +1 more
core   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Estimation of the Distribution of Duration of Breastfeeding from Cross-Sectional Data: Some Methodological Issue.

Journal of Biostatistics and Epidemiology, 2021
Background: Duration of breastfeeding is an important health indicator of mother and child. There are various indirect epidemiological methods available to estimate the duration of breastfeeding from cross sectional data.
Anup Kumar, Sachin Kumar, Jai Kishun, Uttam Singh, Pushpraj Pushpraj   +4 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Bias and precision of methods for estimating the difference in restricted mean survival time from an individual patient data meta-analysis

BMC Medical Research Methodology, 2016
Background The difference in restricted mean survival time ( rmstD t ∗ $$ rmstD\left({t}^{\ast}\right) $$ ), the area between two survival curves up to time horizon t ∗ $$ {t}^{\ast } $$ , is often used in cost-effectiveness analyses to estimate the ...
Béranger Lueza, Federico Rotolo, Julia Bonastre, Jean-Pierre Pignon, Stefan Michiels   +4 more
doaj   +1 more source

Doubly robust estimator of risk in the presence of censoring dependent on time-varying covariates: application to a primary prevention trial for coronary events with pravastatin

BMC Medical Research Methodology, 2020
Background In the presence of dependent censoring even after stratification of baseline covariates, the Kaplan–Meier estimator provides an inconsistent estimate of risk.
Takuya Kawahara, Tomohiro Shinozaki, Yutaka Matsuyama   +2 more
doaj   +1 more source