Results 51 to 60 of about 220,037 (330)
A note on the estimation of confidence intervals for cost-effectiveness when costs and effects are censored [PDF]
, 2002 <i>Background</i>. The relation between methodological advances in estimation of confidence intervals (CIs) for incremental cost-effectiveness ratios (ICER) and estimation of cost effectiveness in the presence of censoring has not been ...
Blackhouse, G. +2 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Berry-Esseen Type Bound in Kernel Density Estimation for Negatively Associated Censored Data
Journal of Applied Mathematics, 2013 We discuss the kernel estimation of a density function based on censored data when the survival and the censoring times form the stationary negatively associated (NA) sequences.
Qunying Wu, Pingyan Chen
doaj +1 more source
Kaplan-Meier V- and U-statistics
, 2020 In this paper, we study Kaplan-Meier V- and U-statistics respectively defined as $\theta(\widehat{F}_n)=\sum_{i,j}K(X_{[i:n]},X_{[j:n]})W_iW_j$ and $\theta_U(\widehat{F}_n)=\sum_{i\neq j}K(X_{[i:n]},X_{[j:n]})W_iW_j/\sum_{i\neq j}W_iW_j$, where $\widehat{
Fernández, Tamara, Rivera, Nicolás
core +1 more source
Mean Survival Time from Right Censored Data [PDF]
, 2009 A nonparametric estimate of the mean survival time can be obtained as the area under the Kaplan-Meier estimate of the survival curve. A common modification is to change the largest observation to a death time if it is censored.
Hess, Kenneth R, Zhong, Ming
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Kaplan-Meier Estimate on the Plane
The Annals of Statistics, 1988 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Survival Analysis Using Auxiliary Variables Via Nonparametric Multiple Imputation [PDF]
, 2004 We develop an approach, based on multiple imputation, that estimates the marginal survival distribution in survival analysis using auxiliary variable to recover information for censored observations.
Commenges, Daniel +3 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source