Results 71 to 80 of about 31,905 (253)

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]

PLoS ONE, 2014
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock, Qi Ma, Biju Issac, Enrique A Mesri   +3 more
doaj   +1 more source

Zosteriform Primary Cutaneous Marginal Zone Lymphoma—A Case Report

Australasian Journal of Dermatology, EarlyView.
ABSTRACT We report a case of zosteriform PCMZL presenting in a T3–T4 dermatomal distribution not previously described in the literature. Although the varicella zoster virus was not detected in this case, late diagnosis of the acute eruption of zoster or even preceding zoster ‘sine herpete’ cannot be excluded as antigenic triggers.
Natalie Teh, Lachlan Byth, Victor Loh, Mrudula Krishnaswamy, Samuel Zagarella   +4 more
wiley   +1 more source

Epidemiology of AIDS in Malta [PDF]

, 1996
The occurrence, frequency, distribution and determinants of HIV and AIDS are described for Maltese residents. Up to 30 June 1996, 38 notifications of AIDS were received by the Public Health Department (36 in males), 35 died.
Amato-Gauci, Andrew J., Vella, K.A.
core  

NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]

, 2015
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
A Sarikas, A Yaron, Adrian Whitehouse, AF Kisselev, AS Turnell, B Romani, Belinda Baquero-Pérez, BR Jackson, BR Jackson, Brian R. Jackson, C Grossmann, C Simonelli, CC Rossetto, David J. Hughes, DE de Oliveira, DF Lee, DJ Goodwin, DJ Stanley, DP Dittmer, E Boulanger, EA Mesri, EJ Bennett, F Gould, G Jubelin, G Rabut, H Karttunen, H Matta, H Nakamura, HC Jha, HJ Brown, J Hannah, J Jin, Jennifer J. Wood, JM O'Dowd, JR Boyne, KA Sarosiek, Klaus Früh, KR Alkharsah, KT Hall, L La Ferla, M Karin, M Pearce, MA Milhollen, MA Milhollen, O Vieira J, P Wimmer, QL Cai, R Sun, RD Everett, S Bhatt, S Gantt, S Gastaldello, SP Jackson, T Ma, T Nakagawa, TA Soucy, TA Soucy, V Majerciak, W Bu, W Chen, X Lei, X Yu, Y Izumiya, Y Wang, Y Wang   +64 more
core   +3 more sources

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma in Brazil

Brazilian Journal of Medical and Biological Research, 2006
Kaposi's sarcoma (KS) became a critical health issue with the emergence of acquired immunodeficiency syndrome (AIDS) in the 1980s. Four clinical-epidemiological forms of KS have been described: classical KS, endemic KS, iatrogenic KS, and AIDS-associated
S. Ramos-da-Silva, D. Elgui-de-Oliveira, L. Borges, C.E. Bacchi   +3 more
doaj   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

To reactivate or not to reactivate : Control of KSHV lytic replication is essential for apoptosis in response to p53 restoration [PDF]

, 2010
Kaposi's sarcoma herpesvirus (KSHV) is an oncogenic human virus and the causative agent of three human malignancies: Kaposi's sarcoma (KS), Multicentric Castleman's Disease (MCD), and primary effusion lymphoma (PEL).
Sarek, Grzegorz
core  

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source